• Produktbild: The Islets of Langerhans
  • Produktbild: The Islets of Langerhans
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The Islets of Langerhans

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

28.05.2012

Abbildungen

XX, 798 p.

Herausgeber

Md. Shahidul Islam

Verlag

Springer Netherland

Seitenzahl

798

Maße (L/B/H)

23,5/15,5/4,4 cm

Gewicht

1218 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-94-007-3194-3

Beschreibung

Rezension

"It looks very comprehensive and covers all current areas of interest and includes chapters written by world renowned contributors - very nice!"



Matthias von Herrath, MD




Professor and Director, Center for Type 1 Diabetes Research



La Jolla Institute for Allergy and Immunology,



La Jolla

CA, USA


"This book will be welcomed by islet researchers and clinicians interested in the latest developments and theories from which new therapeutics for diabetes can emerge". 



Martha Pavlakis, MD




Associate Professor of Medicine, Harvard Medical School



Medical Director, Kidney and Pancreas Transplantation



Beth Israel Deaconess Medical Center



Boston, MA, USA


"The field of islet biology is assuming increasing importance with the recognition that beta-cell dysfunction is a critical feature of type II diabetes. Improving b-cell function and/or b-cell mass may be the best approach to treating diabetes. Thus, the publication of a book covering so many aspects of this field is timely". 



Fred Levine, M.D., Ph.D.




Professor, Burnham Institute for Medical Research



Director, Sanford Children's Health Research Center



La Jolla, CA, USA


 "The growing prevalence of both type 1 and type 2 diabetes make islet cell biology a critical concern for a wide range of scientists and health professionals. From anatomy and developmental biology, through islet physiology and biochemistry, to issues of immunology and transplantation, this book is a terrific resource".



Jonathan M.W.Slack, Ph.D., F.Med.Sci.




Director, Stem Cell Institute, University of Minnesota,



Medical School



Minneapolis, MN,  USA


"This book allows you to enjoy an adventurous and instructive guided tour in the archipelago of the islets of Langerhans. A team of expert and enthusiastic explorers will not only conduct the voyager through almost all niches of this complex and fascinating environment, butalso provide him with clues and keys for future exploration of still hidden sites".



Prof. Pellegrino Masiello




Dept. of Experimental Pathology,



University of Pisa,



Pisa, Italy


"The pancreatic islet is a complex mini-organ whose dysfunction is critical in all forms of diabetes.  This book provides a comprehensive review of the molecular and cellular processes in islet development, gene expression, and physiology and reviews how a better understanding of the pancreatic islet will advance efforts to develop new therapeutic approaches for diabetes.  This book should be quite useful for anyone interested in the pancreatic islet or diabetes".



Alvin C. Powers, M.D.




Joe C. Davis Chair in Biomedical Science



Professor of Medicine, Molecular Physiology and Biophysics



Director, Vanderbilt Diabetes Center



Vanderbilt University



Nashville, TN




USA


"A very timely book on the Islet of Langerhans that coincides with the realization that pancreatic ß-cell failure is key to all forms of diabetes mellitus and research in the field is exploding. It contains very thoughtful chapters, each by renown experts in their field, and tackles the complexity of this micro-organ in health and disease very comprehensively and thoughtfully. It will likely become a Reference for years to come for basic researchers, clinicians and students interested is diabetes research"



Marc Prentki, PhD




Professor of Nutrition and Biochemistry



Canada Research Chair in Diabetes and Metabolism



MDRC Director



Montreal, QC



Canada





 

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

28.05.2012

Abbildungen

XX, 798 p.

Herausgeber

Md. Shahidul Islam

Verlag

Springer Netherland

Seitenzahl

798

Maße (L/B/H)

23,5/15,5/4,4 cm

Gewicht

1218 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-94-007-3194-3

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: The Islets of Langerhans
  • Produktbild: The Islets of Langerhans
  • Microscopic Anatomy of the Human Islet of Langerhans.- The Comparative Anatomy of Islets.- Approaches for Imaging Islets: Recent Advances and Future Prospects.- Islet Cell Development.- High Fat Programming of ?-Cell Failure.- Nutrient Regulation of Insulin Secretion and ?-Cell Functional Integrity.- Electrophysiology of Islet Cells.- ATP-Sensitive Potassium Channels in Health and Disease.- Role of Mitochondria in ?-cell Function and Dysfunction.- Basement Membrane in Pancreatic Islet Function.- Calcium Signaling in the Islets.- Electrical Bursting, Calcium Oscillations, and Synchronization of Pancreatic Islets.- Cyclic AMP Signaling in Pancreatic Islets.- Exocytosis in Islet ?-Cells.- The Novel Roles of Glucagon-Like Peptide-1, Angiotensin II, and Vitamin D in Islet Function.- Proteomics and Islet Research.- Wnt Signaling in Pancreatic Islets.- Molecular Pathways Underlying the Pathogenesis of Pancreatic ?-Cell Dysfunction.- Mechanisms of Pancreatic ?-Cell Apoptosis in Diabetes and Its Therapies.- ?-Cell Function in Obese-Hyperglycemic Mice [ob/ob Mice].- Islet Structure and Function in the GK Rat.- The ?-Cell in Human Type 2 Diabetes.- Clinical Approaches to Preserve ?-Cell Function in Diabetes.- Immunology of ?-Cell Destruction.- Toll-Like Receptors and Type 1 Diabetes.- Prevention of ?-Cell Destruction in Autoimmune Diabetes: Current Approaches and Future Prospects.- In Vivo Regeneration of Insulin-Producing ?-Cells.- Customized Cell-Based Treatment Options to Combat Autoimmunity and Restore ?-Cell Function in Type 1 Diabetes Mellitus: Current Protocols and Future Perspectives.- The Programmable Cell of Monocytic Origin (PCMO): A Potential Adult Stem/Progenitor Cell Source for the Generation of Islet Cells.- Islet Isolation for ClinicalTransplantation.- Human Islet Autotransplantation: The Trail Thus Far and the Highway Ahead.- Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes.- Successes and Disappointments with Clinical Islet Transplantation.- Islet Cell Tumours.