• Produktbild: The Islets of Langerhans
  • Produktbild: The Islets of Langerhans
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The Islets of Langerhans

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

09.04.2010

Herausgeber

Md. Shahidul Islam

Verlag

Springer Netherland

Seitenzahl

798

Maße (L/B/H)

24,1/16/4,9 cm

Gewicht

1379 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-90-481-3270-6

Beschreibung

Rezension

"It looks very comprehensive and covers all current areas of interest and includes chapters written by world renowned contributors - very nice!"

Matthias von Herrath, MD


Professor and Director, Center for Type 1 Diabetes Research

La Jolla Institute for Allergy and Immunology,

La Jolla

CA, USA


"This book will be welcomed by islet researchers and clinicians interested in the latest developments and theories from which new therapeutics for diabetes can emerge". 

Martha Pavlakis, MD


Associate Professor of Medicine, Harvard Medical School

Medical Director, Kidney and Pancreas Transplantation

Beth Israel Deaconess Medical Center

Boston, MA, USA


"The field of islet biology is assuming increasing importance with the recognition that beta-cell dysfunction is a critical feature of type II diabetes. Improving b-cell function and/or b-cell mass may be the best approach to treating diabetes. Thus, the publication of a book covering so many aspects of this field is timely". 

Fred Levine, M.D., Ph.D.


Professor, Burnham Institute for Medical Research

Director, Sanford Children's Health Research Center

La Jolla, CA, USA


 "The growing prevalence of both type 1 and type 2 diabetes make islet cell biology a critical concern for a wide range of scientists and health professionals. From anatomy and developmental biology, through islet physiology and biochemistry, to issues of immunology and transplantation, this book is a terrific resource".

Jonathan M.W.Slack, Ph.D., F.Med.Sci.


Director, Stem Cell Institute, University of Minnesota,

Medical School

Minneapolis, MN,  USA


"This book allows you to enjoy an adventurous and instructive guided tour in the archipelago of the islets of Langerhans. A team of expert and enthusiastic explorers will not only conduct the voyager through almost all niches of this complex and fascinating environment, butalso provide him with clues and keys for future exploration of still hidden sites".

Prof. Pellegrino Masiello


Dept. of Experimental Pathology,

University of Pisa,

Pisa, Italy


"The pancreatic islet is a complex mini-organ whose dysfunction is critical in all forms of diabetes.  This book provides a comprehensive review of the molecular and cellular processes in islet development, gene expression, and physiology and reviews how a better understanding of the pancreatic islet will advance efforts to develop new therapeutic approaches for diabetes.  This book should be quite useful for anyone interested in the pancreatic islet or diabetes".

Alvin C. Powers, M.D.


Joe C. Davis Chair in Biomedical Science

Professor of Medicine, Molecular Physiology and Biophysics

Director, Vanderbilt Diabetes Center

Vanderbilt University

Nashville, TN


USA


"A very timely book on the Islet of Langerhans that coincides with the realization that pancreatic ß-cell failure is key to all forms of diabetes mellitus and research in the field is exploding. It contains very thoughtful chapters, each by renown experts in their field, and tackles the complexity of this micro-organ in health and disease very comprehensively and thoughtfully. It will likely become a Reference for years to come for basic researchers, clinicians and students interested is diabetes research"

Marc Prentki, PhD


Professor of Nutrition and Biochemistry

Canada Research Chair in Diabetes and Metabolism

MDRC Director

Montreal, QC

Canada




 

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

09.04.2010

Herausgeber

Md. Shahidul Islam

Verlag

Springer Netherland

Seitenzahl

798

Maße (L/B/H)

24,1/16/4,9 cm

Gewicht

1379 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-90-481-3270-6

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: GPSR Kontakt

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  • Produktbild: The Islets of Langerhans
  • Produktbild: The Islets of Langerhans
  • CHAPTER 1 : Microscopic anatomy of the human islet of Langerhans - Peter In't Veld and Miriam Marichal
    CHAPTER 2 : The comparative anatomy of islets - Scott Heller
    CHAPTER 3: Approaches for imaging of islets: recent advances and future prospects - Ulf Ahlgren and Martin Gotthardt
    CHAPTER 4: Islet-cell Development - Anabel Rojas, Adrian Khoo, Juan R. Tejedo, Francisco J. Bedoya, Bernat Soria and Franz Martín
    CHAPTER 5: High fat programming of b-cell failure - Marlon. E. Cerf
    CHAPTER 6: Nutrient regulation of insulin secretion and b-cell functional integrity - Philip Newsholme, Celine Gaudel, and Neville H McClenaghan
    CHAPTER 7: Electrophysiology of islet cells - Gisela Drews, Peter Krippeit-Drews and Martina Düfer
    CHAPTER 8: ATP sensitive potassium channels in health and disease - Rebecca Clark and Peter Proks
    CHAPTER 9: Role of mitochondria in b-cell function and dysfunction - Pierre Maechler, Ning Li, Marina Casimir, Laurène Vetterli, Francesca Frigerio, Thierry Brun
    CHAPTER 10: Basement membrane in pancreatic islet function - Martin Kragl and Eckhard Lammert
    CHAPTER 11: Calcium signaling in the islets - Md. Shahidul Islam
    CHAPTER 12: Electrical bursting, calcium oscillations, and synchronization of pancreatic islets - Richard Bertram, Arthur Sherman, and Leslie S. Satin
    CHAPTER 13: Cyclic AMP signaling in pancreatic islets - Brian Furman, Wee Kiat Ong, and Nigel Pyne
    CHAPTER 14: Exocytosis in islet b-cells - Haruo Kasai, Hiroyasu Hatakeyama, Mitsuyo Ohno and Noriko Takahashi
    CHAPTER 15: The novel roles of glucagon-like peptide-1, angiotensin II, and vitamin D in islet function - Po Sing Leung
    CHAPTER 16: Proteomics and islets research - Meftun Ahmed
    CHAPTER 17: Wnt signaling in pancreatic islets - Zhengyu Liu and Joel F. Habener
    CHAPTER 18: Molecular pathways underlying the pathogenesis of pancreatic a-cell dysfunction - Dan Kawamori,Hannah J. Welters, and Rohit N. Kulkarni
    CHAPTER 19: Mechanisms of pancreatic b-cell apoptosis in diabetes and its therapies - James D. Johnson, Dan S. Luciani
    CHAPTER 20: b-cell function in obese-hyperglycaemic mice [ob/ob mice] - Per Lindström
    CHAPTER 21: Islet structure and function in the GK rat - B. Portha, G. Lacraz, A. Chavey, F. Figeac, M. Fradet, C. Tourrel-Cuzin, F. Homo-Delarche, M-H. Giroix, D. Bailbé, MN. Gangnerau, J. Movassat
    CHAPTER 22: The b-cell in human type 2 diabetes - Piero Marchetti, Roberto Lupi, Silvia Del Guerra, Marco Bugliani, Lorella Marselli and Ugo Boggi
    CHAPTER 23: Clinical approaches to preserve b-cell function in diabetes - Bernardo L. Wajchenberg
    CHAPTER 24: Immunology of b-cell destruction - Daria La Torre, and Åke Lenmark
    CHAPTER 25: Toll-like receptors and type 1 diabetes - Danny Zipris
    CHAPTER 26: Prevention of b-cell destruction in autoimmune diabetes: current approaches and future prospects - Saikiran K Sedimbi and Carani B Sanjeevi
    CHAPTER 27: In vivo regeneration of insulin-producing b-cell - Hee-Sook Jun
    CHAPTER 28: Customized cell-based treatment options to combat autoimmunity and restore b-cell function in Type I diabetes mellitus: current protocols and future perspectives - Fred Fändrich and Hendrik Ungefroren
    CHAPTER 29: The progammable cell of monocytic origin (PCMO): A potential adult stem/progenitor cell source for the generation of islet cells - Hendrik Ungefroren and Fred Fändrich
    CHAPTER 30: Islet isolation for clinical transplantation - Tatsuya Kin
    CHAPTER 31: Human islet autotransplantation: the trail thus far and the highway ahead - Martin Hermann, Raimund Margreiter and Paul Hengster
    CHAPTER 32: Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes - Lorenzo Piemonti, Luca G. Guidotti,