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Peptide-Derived Drug Discovery Design Strategies, Discovery Methods and Applications in Therapeutic Challenges

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

01.03.2027

Herausgeber

Jian Zhang

Verlag

Elsevier

Seitenzahl

500

Maße (L/B)

22,9/15,2 cm

Sprache

Englisch

ISBN

978-0-443-45030-3

Beschreibung

Portrait

Professor Jian Zhang is the director of the Center for Medicinal Chemistry and Bioinformatics at Shanghai JiaoTong University School of Medicine in China. His research focuses on drug design, medicinal chemistry, and chemical biology, with groundbreaking achievements in precise target identification and first-in-class drug discovery. He has published more than 150 high-impact journal articles

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

01.03.2027

Herausgeber

Jian Zhang

Verlag

Elsevier

Seitenzahl

500

Maße (L/B)

22,9/15,2 cm

Sprache

Englisch

ISBN

978-0-443-45030-3

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Peptide-Derived Drug Discovery

  • Section 1: Introduction
    1. Peptide-Derived Drug Discovery: Challenges and Solutions

    Section 2: Innovative Methodologies in Peptide Chemistry
    2. Macrocyclic Peptides: Advantages and Future Perspectives
    3. Fast-flow Technology based Rapid Peptide Synthesis.
    4. Chemoselective Ligation-Mediated Peptide Drug Discovery
    5. Structure-based Rational Design Strategies in Peptide Drug Discovery
    6. Carbohydrates in Peptide Drug
    7. Phage Display-Based Discovery of Bicyclic Peptide Drugs
    8. mRNA-Display based Nonstandard Peptide Drug Discovery
    9. Enzymatic Macrocyclization and Peptide Biosynthesis
    10. Peptide-based PROTAC Durg Discovery

    Section 3. Peptide Therapeutics for Challenging and "Undruggable" Targets
    11. Targeting "Undruggable" protein with Peptide-Based Molecules
    12. Insights into Peptide Drug Discovery for G-Protein Coupled Receptors (GPCRs)
    13. Cyclic Cell-Penetrating Peptides for Targeting p53/MDM2 Interactions
    14. Recent Advances in Targeting KRas
    15. Cell-Penetrating Bicyclic Peptide Targeting SARS-CoV¿2

    Section 4. Recent Advances in Approved Peptide Therapeutics
    16. Recently Approved Peptide Therapeutics
    17. Peptide Drug: From Discovery to Approval Index