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Produktbild: Clinical Xenotransplantation
Vorbesteller Neu

Clinical Xenotransplantation Pathways and Progress in the Transplantation of Organs and Tissues Between Species

146,99 €

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

26.12.2026

Abbildungen

I, 542 p. 77 illus., 69 illus. in color.

Herausgeber

Raphael P. H. Meier + weitere

Verlag

Springer

Seitenzahl

542

Maße (B/H)

17,8/25,4 cm

Auflage

Second Edition 2026

Sprache

Englisch

ISBN

978-3-032-35121-0

Beschreibung

Portrait

Raphael P. H. Meier, MD, PhD, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA 

Burcin Ekser, MD, PhD, Division of Transplant Surgery, Department of Surgery, Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA 

Prof. Leo Bühler, Department of Surgery, Fribourg Cantonal Hospital, University of Fribourg, Fribourg Switzerland

David K. C. Cooper, MD, PhD, Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical School, Pittsburgh, PA, USA.

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

26.12.2026

Abbildungen

I, 542 p. 77 illus., 69 illus. in color.

Herausgeber

Verlag

Springer

Seitenzahl

542

Maße (B/H)

17,8/25,4 cm

Auflage

Second Edition 2026

Sprache

Englisch

ISBN

978-3-032-35121-0

Herstelleradresse

Springer International Publishing AG
Gewerbestr. 11
6330 Cham
Schweiz
Url: www.springer.com

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  • Produktbild: Clinical Xenotransplantation

  • Part 1    Background and Current State of Clinical Xenotransplantation .- 1. Clinical Pig Organ Xenotransplantation: An Introduction.- 2. Summary of Recent Progress in Clinical Xenotransplantation and the International Human Xenotransplantation Inventory.- Part 2 The Innate Immune Response to a Pig Xenograft .- 3. Overview of the Innate Immune Response to a Pig Xenograft.- 4. Xenoreactive Antibodies in Xenotransplantation.- 5. The Complement Cascade in Xenotransplantation.- 6. Coagulation in Xenotransplantation: The Central Role of the Graft Endothelium.- 7. Emerging Insights into the Role of Natural Killer (NK) Cells in Xenotransplantation.- 8. Macrophages in Xenotransplantation.- 9. New methods of detecting the innate immune response to a xenograft.- 10. Differences in the Response between NHPs and Humans.- Part 3 Gene-edited Pigs .- 11. How Many Gene-edits Are Necessary for Xenogeneic Heart Transplantation?.- 12. How Many Gene-edits Are Necessary for Xenogeneic Kidney Transplantation?.- Part 4 The Adaptive Immune Response to a Pig Xenograft .- 13. The T Cell Response in Pig-to-human Xenotransplantation.- 14. The B Cell Response in Pig-to-human Xenotransplantation.- Part 5 Immunosuppressive Therapy .- 15. Immunosuppressive therapy to prevent the adaptive immune response.- Part 6 Sensitization to HLA and SLA .- 16. Cross-reactivity between HLA and SLA.- 17. Is sensitization to HLA detrimental to Xenotransplantation? 18. Is Sensitization to SLA Detrimental to Subsequent Allotransplantation?.- Part 7 Kidney Xenotransplantation .- 19. The Status of Preclinical Studies of Kidney Xenotransplantation in Pig-to-NHP Models.- 20. Histopathology of Kidney Graft Rejection.- 21. Function of Pig Kidneys in NHPs and Humans.- 22. Clinical Experience 1: The NYU Clinical Experience.- 23. Clinical Experience 2: The NYU Clinical Experience.- 24. Storage of the pig kidney.- Part 8 Heart Xenotransplantation .- 25. The Status of Preclinical Studies of Heart Xenotransplantation in Pig-to-NHP Models.- 26. Histopathology of Heart Graft rejection.- 27. Considerations in the selection of adult patients for gene-edited pig cardiac Xenotransplantation.- 28. Clinical experience of Heart Xenotransplantation.- 29. Bridging to Allotransplantation by a Pig Heart in Infants.- 30. Storage of the pig heart.- Part 9 Liver Xenotransplantation .- 31. The Status of Preclinical Studies of Liver Xenotransplantation in Pig-to-NHP Models.- 32. Bridging to allotransplantation by ex vivo pig liver perfusion.- 33. Storage of the pig liver.- 34. Clinical Considerations in Pig Liver Xenotransplantation.- Part 10 Lung Xenotransplantation .- 35. The Status of Preclinical Studies of Lung Xenotransplantation in Pig-to-NHP Models.- Part 11 Pancreatic Islet Xenotransplantation .- 36. The Status of Preclinical Studies of Pancreatic Islet Xenotransplantation in Pig-to-NHP Models.- 37. What are the ideal porcine islets for Clinical Xenotransplantation?.- 38. Ex Vivo Testing of Xenogeneic Islets.- 39. Xenogeneic Islet Macroencapsulation.- 40. Enhancing Pig Insulin Production.- 41. Clinical Considerations of Pancreatic Islet Xenotransplantation.- Part 12 Corneal Xenotransplantation .- 42. The Status of Preclinical Studies of Corneal Xenotransplantation in Pig-to-NHP Models.- 43. Clinical Considerations of Corneal Xenotransplantation.- Part 13 Red Blood Cell Xenotransfusion .- 44. The Status of Preclinical Studies of Red Blood Cell Xenotransfusion in Pig-to-NHP Models.- 45. Clinical Considerations of Red Blood Cell Xenotransfusion.- Part 14 Skin Xenotransplantation .- 46. The Status of Preclinical Studies of Skin Xenotransplantation in Pig-to-NHP Models.- 47. Clinical considerations of Skin Xenotransplantation.- Part 15 Xenotransplantation in Decedents .- 48. The Pros of Xenotransplantation Studies in Decedents.- 49. The cons of Xenotransplantation studies in decedents.- Part 16 Potential Methods of Inducing Tolerance to a Xenograft .- 50. Thymus transplantation.- 51. Other potential approaches to Tolerance induction in Xenotransplantation.- Part 17 Preventing and Treating Potential Infectious Complications .- 52. Preventing potential infectious complications in Xenotransplantation.- 53. Breeding and Housing Pigs in a Designated Pathogen-free Environment.- 54. Diagnosing and Treating Potential Infections in Recipients of Pig Grafts.- 55. Porcine endogenous retroviruses.- Part 18 Tissue Xenotransplantation and Regenerative Medicine .- 56. The potential of regenerative medicine using pig tissues.- Part 19 Regulation, Ethical, Legal, Religious, Social and Financial Aspects .- 57. Informed consent in Xenotransplantation.- 58. Ethical aspects of Clinical Xenotransplantation of practical importance.- 59. Legal aspects of Clinical Xenotransplantation.- 60. Religious attitudes to Clinical Xenotransplantation.- 61. Public perceptions of Clinical Xenotransplantation.- 62. Economic aspects of Xenotransplantation.- 63. A biotechnology industry perspective on Xenotransplantation.- Part 20 Global Xenotransplantation Research .- 64. Xenotransplantation Research in Australasia.- 65. Xenotransplantation Research in China.- 66. Xenotransplantation Research in Europe.- 67. Xenotransplantation Research in Japan.- 68. Xenotransplantation Research in North America.- 69. Xenotransplantation Research in South Korea.- Part 21 Future of Xenotransplantation .- 70. What does the future hold in Xenotransplantation? Potential progress and potential problems.