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Produktbild: Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside
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Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside

276,99 €

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

31.12.2026

Herausgeber

Jose Jalife + weitere

Verlag

Elsevier

Seitenzahl

1200

Maße (L/B)

27,6/21,6 cm

Gewicht

450 g

Auflage

9th edition

Sprache

Englisch

ISBN

978-0-443-37947-5

Beschreibung

Portrait

Distinguished Senior Investigator, Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain. Emeritus Professor of Internal Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.

Dr Jalife is also actively conducting research at the Centro Nacional de Investigaciones Cardiovasculares, in Madrid, Spain. William Gregory Stevenson, MD, is Professor of Medicine at Vanderbilt University School of Medicine in Nashville, Tennessee. Dr Jalife will assume the role of lead editor on the 8th edition with Douglas Zipes's retirement

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

31.12.2026

Herausgeber

Verlag

Elsevier

Seitenzahl

1200

Maße (L/B)

27,6/21,6 cm

Gewicht

450 g

Auflage

9th edition

Sprache

Englisch

ISBN

978-0-443-37947-5

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside
  • Part I: Structural and Molecular Bases of Ion Channel Function
    1. Voltage-Gated Sodium Channels and Electrical Excitability of the Heart
    2. Voltage-Gated Calcium Channels
    3. Voltage-Gated Potassium Channels
    4. Molecular Regulation of Cardiac Inward Rectifier Potassium Channel
    5. Mammalian Calcium Pumps in Health and Disease
    6. Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function
    7. Organellar Ion Channels and Transporters
    8. Molecular Organization, Gating, and Function of Connexin-Based Gap Junction Channels and Hemichannels

    Part II: Biophysics of Cardiac Ion Channel Function
    9. Voltage-Gated Sodium Channels with Open and Closed Gates: Implications for State-Dependent Drug Design
    10. Regulation of Cardiac Calcium Channels
    11. Molecular Genetics of ATP-Sensitive K+ Channels in Cardiovascular Diseases
    12. Role of Enhancers in Transcriptional Regulation of Cardiac Electrical Activity
    13. Notch-Mediated Transcriptional and Epigenetic Regulation of Cardiac Ion Channels
    14. Stretch-Activated Potassium Channels in the Human Heart: Pathophysiologic and Clinical Significance
    15. Connexins and Pannexins in Cardiovascular Disease
    16. Excitation-Contraction Coupling

    Part III: Intermolecular Interactions and Cardiomyocyte Electrical Function
    17. Ion Channel Trafficking in the Heart
    18. Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5
    19. Connecting Cardiac Excitation to the Atomic Interactions of Ion Channels
    20. Macromolecular Complexes and Cardiac Potassium Channels
    21. Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias
    22. The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion and Cell Excitability
    23. Function and Dysfunction of Ion Channel Membrane Trafficking and Post Translational Modification
    24. Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling

    Part IV: Cell Biology of Cardiac Impulse Initiation and Propagation
    25. Coupled Oscillators and Sinoatrial Pacemaker Activity
    26. Optical Mapping of Cardiac Action Potentials in Zebrafish to Assess Genetic Variants
    27. Cell-to-Cell Communication and Impulse Propagation
    28. Mechanisms of Normal and Dysfunctional Sinoatrial Nodal Excitability and Propagation
    29. Cell Biology of the Specialized Cardiac Conduction System

    Part V: Models of Cardiac Excitation
    30. Prediction of Drug-Induced Arrhythmia Using Machine Learning
    31. Global Optimization Approaches to Generate Dynamically Robust Electrophysiological Models
    32. Calcium Signaling in Cardiomyocyte Models with Realistic Geometries
    33. Theory of Rotors and Arrhythmias
    34. Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associate With Arrhythmic Risk Markers
    35. Computational Approaches for Accurate Rotor localization in the Human Atria
    36. Modeling the Aging Heart
    37. Electromechanical Vortex Filaments During Cardiac Fibrillation

    Part VI: Neural Control of Cardiac Electrical Activity
    38. Innervation of the Sinoatrial Node
    39. Mechanisms for Altered Autonomic and Oxidant Regulation of Cardiac Sodium Currents
    40. Neural Activity and Atrial Tachyarrhythmias
    41. Sympathetic Modulation of Cardiac Electrophysiology
    42. Role of the Autonomic Nervous System in Atrial Fibrillation

    Part VII: Arrhythmia Mechanisms
    43. Rotors in Human Atrial Fibrillation
    44. Nonivasive Frequency-Phase Mapping of Atrial Fibrillation
    45. Electrical Biomarkers of the Progression of Atrial Fibrillation
    46. Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation
    47. Genetics of Atrial Fibrillation

    Part VIII: Molecular Genetics and Pharmacogenomics
    48. Mechanisms in Heritable Sodium Channel Diseases
    49. Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes
    50. Inheritable Potassium Channel Diseases
    51. Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation

    Part IX: Pharmacologic, Genetic, and Cell Therapy of Ion Channel Dysfunction
    52. Upstream therapy to prevent AF progression
    53. Pharmacogenomics of Cardiac Arrhythmias
    54. Screening Drugs for Myocardial Disease in Vivo with Zebrafish
    55. Gene Therapy for Atrial Fibrillation

    Part X: Cell biology and electrophysiology of human induced pluripotent stem cell derived cardiomyocytes
    56. Cardiac Remodeling and Regeneration
    57. High-Throughput Optical Mapping of 2 and 3-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing
    58. Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors
    59. Functional Co-Culture of Sympathetic Neurons and Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

    Part XI: Diagnostic Evaluation
    60. Assessment of the Patient With a Cardiac Arrhythmia
    61. Differential Diagnosis of Narrow and Wide Complex Tachycardias
    62. Electrocardiographic Monitoring: Short, Long-Term Recording
    63. Personal Cardiac Monitoring
    64. Computed Tomography for Electrophysiology
    65. Magnetic Resonance Imaging for Electrophysiology
    66. Intracardiac Echocardiography for Electrophysiology
    67. Autonomic Nervous System Assessment for Syncope and Arrhythmia Risk
    68. Non-invasive Electrocardiographic Imaging of Arrhythmogenic Substrates and Arrhythmias
    69. Genetic Testing

    Part XII: Supraventricular Arrhythmias: Diagnosis and Therapy
    70. Supraventricular Tachycardias: Diagnostic Maneuvers in the Electrophysiology Laboratory
    71. Atrial Tachycardia
    72. Atrioventricular Nodal Reentrant Tachycardia
    73. Junctional Tachycardia
    74. Preexcitation, Atrioventricular Reentry, Variants
    75. Atrial Fibrillation: Mechanisms, Clinical Features, and Management
    76. Ablation for Atrial Fibrillation
    77. Left Atrial Appendage Management
    78. Typical and Atypical Atrial Flutter: Mapping and Ablation

    Part XIII: Ventricular Arrhythmias
    79. Sudden Cardiac Death in Adults
    80. Premature Ventricular Complexes
    81. Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management
    82. PVC Ablation with Anatomic Guidance: Papillary Muscle, Moderator Band and Valve Annulus Sites
    83. Fascicular Ventricular Arrhythmias
    84. Bundle Branch Reentry Tachycardia
    85. Ventricular Arrhythmias in Ischemic Heart Disease
    86. Ablation of Post-Myocardial Infarction VT
    87. Ventricular Tachycardia in Patients with Dilated Cardiomyopathy
    88. Lamin A/C, Noncompaction and Other Genetic Cardiomyopathies with Ventricular Arrhythmias
    89. Ventricular Arrhythmias in Hypertrophic Cardiomyopathy: Sudden Death, Risk Stratification, and Prevention With Implantable Defibrillators
    90. Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
    91. Catecholaminergic Polymorphic Ventricular Tachycardia
    92. Arrhythmias and Conduction Disturbances in Noncompaction Cardiomyopathy
    93. Ventricular Arrhythmias in Takotsubo Cardiomyopathy
    94. Mitral Valve Prolapse, ventricular arrhythmias and Sudden Death
    95. Brugada Syndrome
    96. Long and Short QT Syndromes
    97. Andersen-Tawil Syndrome
    98. Timothy Syndrome
    99. J-Wave Syndromes
    100. Idiopathic Ventricular Fibrillation
    101. Mapping and Ablation of Ventricular Fibrillation
    102. Drug-Induced Ventricular Arrhythmias

    Part XIV: Syncope and Bradyarrhythmias
    103. Syncope
    104. Sinus Node Abnormalities
    105. Postural Orthostatic Tachycardia Syndrome
    106. Atrioventricular Block

    Part XV: Arrhythmias in Special Populations
    107. Sex Differences in Arrhythmias
    108. Sudden Cardiac Deaths in Athletes, Including Commotio Cordis
    109. Cardiac Sarcoidosis
    110. Sleep-Disordered Breathing and Arrhythmias
    111. Ventricular Assist Devices and Cardiac Transplantation Recipients
    112. Arrhythmia in Neurologic Disease
    113. Cancer Therapy Related Arrhythmias

    Part XVI: Congenital Heart Disease and Pediatrics
    114. Arrhythmias in the Pediatric Population
    115. Supraventricular Tachycardias in Congenital Heart Disease
    116. Ventricular Arrhythmias in Congenital Heart Disease

    Part XVII: Pharmacologic Therapy
    117. Antiarrhythmic Drugs
    118. Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death
    119. Oral Anticoagulants

    Part XVIII: Devices for Arrhythmia Management
    120. Implantable Pacemakers
    121. Implantable Cardioverter Defibrillators: Technical Aspects
    122. Implantable Cardioverter Defibrillators: Clinical Aspects
    123. Subcutaneous Implantable Cardioverter Defibrillators
    124. Wearable Defibrillators
    125. Cardiac Resynchronization Therapy
    126. Management of Implanted Device Infections

    Part XIX: Catheter and Surgical Mapping and Ablation
    127. Electrogram Recording and Signal Processing
    128. Electroanatomic Mapping for Arrhythmias
    129. Mapping Scar-Related Arrhythmias
    130. Radiofrequency Ablation
    131. Cryoablation and Other Radiofrequency Alternatives
    132. Transvascular Ethanol Ablation
    133. Stereotactic Radioablation
    134. Percutaneous Epicardial Access, Mapping and Ablation
    135. Surgery for Atrial Fibrillation and Other Supraventricular Tachycardias
    136. Surgery for Ventricular Arrhythmias
    137. Neuromodulation for the Treatment of Arrhythmias