Beschreibung
Produktdetails
Format
Kopierschutz
Nein
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
23.08.2025
Herausgeber
Dalapathi Gugulothu + weitereVerlag
Springer Nature SingaporeSeitenzahl
368 (Printausgabe)
Dateigröße
16518 KB
Sprache
Englisch
EAN
9789819502219
The book presents a comprehensive summary of the advances in methods, applications and challenges in Freeze-drying Technology for pharmaceutical product development.
Freeze drying, sometimes referred to as lyophilization, is an essential method in biomedical and pharmaceutical industries that allows for extremely accurate preservation of sensitive biological components. This book highlights freeze drying operation, the different types of freeze-dryers, development of the freeze-drying cycle, and characterization of freeze-dried goods. It also explores the crucial connection between freeze drying and colloidal dispersions' stability, illuminating the complex interactions between formulation composition, processing variables, and stability of the final product. It focuses on the benefits of this method for stabilizing essential biopharmaceuticals such as probiotics, recombinant proteins and monoclonal antibodies by preventing aggregation and degradation and sustaining their therapeutic effectiveness for longer periods of time. Apart from the chemistry, operations and benefits, this book explores new possibilities for precisely and deeply describing freeze-dried products by discussing the most recent developments in analytical methods.
The audience for this book will comprise of researchers, clinicians, graduate students, and professionals in biotechnology and pharmaceutical industries. This book also serves as a valuable resource for educators by providing them information that they can incorporate into their curricula for teaching pharmaceutical formulation and drug delivery.
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