Table of Contents
Section 1- Biology of Immune Cells
Ch 1 B cells in aging, age-associated diseases and stem cell transplantation
Ch 2 T cell biology: changes with disease, aging, and hematopoietic stem cell transplantation
Ch 3 Plasma cells in autoimmunity
Ch 4 CAR T cells for Autoimmunity
Ch 5 Regulatory T cells for the treatment of autoimmune diseases
Ch 6 Mesenchymal Stromal Cells Derived Extracellular Vesicles
Section 2 - Biology of Stem Cells
Ch 7 Induced Pluripotent Stem Cells: the story of genetic reprogramming
Ch 8 Mesenchymal stromal cell biology and clinical application
Ch 9 Neural Stem Cell Biology
Ch 10 Hematopoietic stem cells: Hierarchical versus Continuum
Ch 11 Biology of Umbilical Cord Blood Cells
Section 3 - Regulatory requirements
Ch 12 Quality, Accreditation, and Regulation in HSCT and Cellular Therapy for Autoimmune Diseases
Ch 13 EUROPEAN PERSPECTIVE ON CELLULAR THERAPY: GOOD TISSUE PRACTICE (GTP) VERSUS GOOD MANUFACTURING PRACTICE (GMP).
Ch 14 GMP Facility Requirements in the United States of America
Section 4 - Mesenchymal Stem Cells for Immune Diseases
Ch 15 Mesenchymal stromal cell therapy for acute graft versus host disease - from bench to clinical approval
Ch 16 Adipose-Derived Stem Cells for Systemic Sclerosis Digital Ulcers
Ch 17 Musculoskeletal stromal/progenitor cells-based cell therapy for Rheumatoid Arthritis (RA)
Ch 18 Mesenchymal Stromal cells for Systemic Sclerosis
Ch 19 Mesenchymal stem cells (MSC) for systemic lupus erythematosus (SLE)
Ch 20 Mesenchymal stem/stromal cells for multiple sclerosis and other neurological diseases
Ch 21 Mesenchymal stromal cells for perianal fistulizing crohn's disease
Ch 22 Umbilical Cord Blood or Mesenchymal Stromal Cells as Potential Therapies for Autism Spectrum Disorder
Section 5 - General concepts: HSCT for Autoimmune Diseases
Ch 23 Animal models of bone marrow transplantation for autoimmune diseases
Ch 24 Autologous HSCT conditioning regimens for autoimmune diseases
Ch 25 Immune reconstitution after hematopoietic stem cell transplantation in autoimmune disease
Ch 26 Microbiota and immune response
Ch 27 Infectious complications in patients undergoing HSCT for autoimmune diseases.
Ch 28 Early Toxicity and Supportive Care of HSCT for Autoimmune Diseases
Ch 29 Late toxicity and supportive care of patients undergoing haematopoietic cell transplantation for autoimmune diseases
Ch 30 Transfusion Medicine
Ch 31 International Registries Sites / Indications / Activity for HSCT in Autoimmune Diseases: the European Society for Blood and Marrow Transplantation (EBMT) and Center for International Blood and Marrow Transplant Research (CIBMTR)
Ch 32 Hematopoietic stem cell mobilization, collection, apheresis, and harvest procedures
Section 6 - Allogeneic HSCT for Autoimmune disease
Ch 33 Hematopoietic Stem Cell Donor Registries: Search Strategies and HLA Methodologies
Ch 34 Allogeneic HSCT and Graft-versus-Host Disease (GvHD): general principles with reference to autoimmune diseases
Ch 35 Haematopoietic cell transplantation in monogenic autoimmune diseases
Ch 36 Advances In The Pathogenesis And Treatment Of Immune Mediated Aplastic Anemia
Section 7- HSCT for autoimmune disease Multiple Sclerosis
Ch 37 Magnetic Resonance Imaging in Multiple Sclerosis
Ch 38 Multiple Sclerosis
Ch 39 Disease-modifying therapies and supportive care of multiple sclerosis
Ch 40 Autologous hematopoietic stem cell transplantation for Secondary Progressive Multiple Sclerosis
Ch 41 Autologous hematopoietic stem cell transplantation for Relapsing Remitting Multiple Sclerosis
Ch 42 Immune mechanisms of autologous hematopoietic stem cell transplantation for multiple sclerosis
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Ch 43 Basics and interpretation of electrodiagnostic testing
Ch 44 Diagnosis and Differentiation of CIDP from other peripheral polyneuropathies
Ch 45 Hematopoietic stem cell transplantation for chronic inflammatory demyelinating polyradiculoneuropathy
Neuromyelitis Optica
Ch 46 Autologous and Allogeneic HSCT for AQP4-IgG positive Neuromyelitis Optica Spectrum Disorders
Systemic Sclerosis
Ch 47 Systemic Sclerosis
Ch 48 The Systemic Sclerosis Heart
Ch 49 Scleroderma Renal Crisis with special considerations for Autologous Hematopoietic Stem Cell Transplant
Ch 50 Systemic Sclerosis and the Lung
Ch 51 AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION IN SYSTEMIC SCLEROSIS
Crohn Disease
Ch 52 Crohn's Disease: Incidence, Diagnosis, Standard Treatment, Prognosis, Outcome Measures
Ch 53 Hematopoietic Stem cell transplantation an alternative to treat Crohn's disease
Type I Diabetes Mellitus
Ch 54 Hematopoietic Stem Cell Transplantation for Type I Diabetes Mellitus
Systemic Lupus Erythematosus
Ch 55 Hematopoietic stem cell transplantation for systemic lupus erythematosus (SLE)
Celiac Disease
Ch 56 Hematopoietic Stem Cell Transplantation for Refractory Celiac Disease type II
Section 8 - Developing indications for HSCT
Ch 57 Haematopoietic stem cell transplantation for Juvenile Idiopathic Arthritis
Ch 58 Haematopoietic Stem Cell Transplantation for Rheumatoid Arthritis
Ch 59 Hematopoietic Stem Cell Transplantation for Behçet's Syndrome
Ch 60 Hematopoietic Stem Cell Transplantation and Myasthenia Gravis
Ch 61 Autologous Haematopoietic Stem Cell Transplantation in Stiff Person Spectrum Disorder
Ch 62 Hematopoietic Stem Cell Transplant-Based Treatment for Psychiatric Disorders
Ch 63 Hematopoietic Stem Cell Transplantation for Psoriasis and Pemphigus Vulgaris
Section 9 - Ethics and economics
Ch 64 Health Economics of Multiple Sclerosis
Ch 65 Ethics of Stem Cells and Stem Cell Transplantation for Autoimmune diseases
Ch 66 Is Healthcare a Human Right?
Ch 67 Appendices
