Foreword
Introduction
Part 1: Immune Checkpoint Inhibitors in the Clinic
Chapter One: Overview of Anti-CTLA-4 Agents: Ipilimumab and Tremilimumab
Daniel Hartman Johnson and Jianjun Gao
Chapter Two: Overview of PD-1 and PD-L1 Inhibitors
Nikolaos Andreatos, Shailender Bhatia, and Petros Grivas
Chapter Three: Indications and Toxicities of Immune Checkpoint Inhibitor Combinations
Lavinia Spain, Michael A. Postow, James Larkin, and Jeffrey Weber Part 2: Specific Immune Checkpoint Inhibitor Toxicities
Chapter Four: General Principles of Immune-Related Toxicities
Osama E. Rahma and Patrick A. Ott Chapter Five: Dermatological Toxicities: Rash, Mucosal Irritation, and Pruritus
Jennifer Wu and Mario E. Lacouture Chapter Six: Musculoskeletal and Rheumatologic Toxicities
Noha Abdel-Wahab, Clifton O. Bingham III, and Maria Suarez-Almazor Chapter Seven: Immune-Related Gastrointestinal Toxicities
Hamzah Abu-Sbeih, Daniel Johnson, Yinghong Wang Chapter Eight: Pneumotoxicity Associated with Immune Checkpoint Blockades
Vickie R. Shannon Chapter Nine: Immune-Related Endocrinopathies Associated with Immune Checkpoint Inhibitors
Rajeev Sharma, Ha Nguyen, Ramona Dadu Chapter Ten: Neurologic Adverse Events and Neurologic Complications
Haroon Ahmad, Jasmin Jo, Elizabeth Gaughan, Camilo Fadul Chapter Eleven: Cardiovascular Toxicities Related to Immune Checkpoint Inhibitors
Pankit Vachhani, Igor Puzanov, Javid J. Moslehi Chapter Twelve: Renal Toxicities Associated with Immune Checkpoint Inhibitors
Ala Abudayyeh, Maen Abdelrahim, Laurence Albiges Chapter Thirteen: Hematologic Toxicities of Apparent Immune-Related Origins
George L. Chen, Caroline Robert, Alexander M. Lesokhin Chapter Fourteen: Ocular Toxicities Caused by Immune Dysregulation
Liliya Golas and Dimitra Skondra Chapter Fifteen: Safety and Regulation of Immune Checkpoint Inhibitors in Special Patient Populations
Douglas B. Johnson, Ryan Sullivan, Paolo A. Ascierto Chapter Sixteen: Cancer-Related Fatigue in Patients of Immune Checkpoint Inhibitor Therapy
Eric D. Hansen, Michelle Walter, Amy A. Case Chapter Seventeen: Cost Effectiveness and Financial Toxicity in New Cancer Therapies
Christine Kohn, Natalia Shcherbakova, Alberto J. Montero