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Rheumatoid Arthritis Methods and Protocols

Aus der Reihe Methods in Molecular Biology
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Beschreibung

This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug...

Beschreibung

This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug delivery, and new research tools. Written in the highly successful
Methods in Molecular Biology
series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge,
Rheumatoid Arthritis: Methods and Protocols
aims to be a basic manual for clinical researchers who are just getting started in the field of intervention study.

Portrait

Produktdetails

Einband

Gebundene Ausgabe
Erscheinungsdatum

23.09.2018
Abbildungen

IX, 253 p. 59 illus., 34 illus. in color.
Herausgeber Shuang Liu

Produktdetails

Einband

Gebundene Ausgabe
Erscheinungsdatum

23.09.2018
Abbildungen

IX, 253 p. 59 illus., 34 illus. in color.
Herausgeber Shuang Liu
Verlag Springer Us
Seitenzahl

253
Maße (L/B/H)

26/18,3/2,1 cm
Gewicht

643 g
Auflage

1st ed. 2018
Sprache

Englisch
ISBN

978-1-4939-8801-3
Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Rheumatoid Arthritis
  • Produktbild: Rheumatoid Arthritis

  • Collagen-induced Arthritis Models.- Human Xenograft Model.- Long-term Constant Subcutaneous Drug Administration.- Clinical Scoring of Disease Activity in Animal Models.- Histological Analysis of Arthritic Joints.- Preparation of Joint Extracts.- Production of Immunizing Antigen Proteoliposome Using Cell-free Protein Synthesis System.- Re-construction of Protein/Liposome Complex.- Production of Neutralizing Antibody.- Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen.- Generation of Specific Aptamers.- Production of Lentiviral Particles.- RNA Interference Ex Vivo.- Lentiviral-mediated Systemic RNA Interference
    in vivo.- 
    Mesenchymal Stem Cell Engineering.- Screening of Ca
    2+
    Influx in Lymphocytes.- Single-cell Ca
    2+
    Imaging.- Electrophysiological Methods to Measure Ca
    2+
    Current.- The Functional Assessment of T cells.- Release of Antibodies and Cytokines from B cells.- Evaluation of Autoreactive Responses.- Bone-resorption Activity in Mature Osteoclasts.- Animal Models of Vasculitis.- Design an Intervention Study.- Assessment of Disease Activity, Structural Damage, and Function in Rheumatoid Arthritis.