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  • Produktbild: Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Produktbild: Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.06.2016

Herausgeber

Thomas Lehner + weitere

Verlag

Academic Press

Seitenzahl

796

Maße (L/B/H)

28,2/22/4,8 cm

Gewicht

2310 g

Sprache

Englisch

ISBN

978-0-12-800105-9

Beschreibung

Portrait

Dr. Thomas Lehner is the Director of the Office for Genomics Research Coordination at the National Institute of Mental Health (NIMH), National Institutes of Health (NIH). He oversees and coordinates all efforts associated with genomics research for the NIMH and is the principal advisor to the NIMH Director and the NIMH Scientific Director for issues related to genetics and genomics. A native of Vienna, Austria, he received a Ph.D. in genetics from the University of Vienna and an MPH in Epidemiology from Columbia University. Since joining NIMH in 2004 Thomas has been instrumental in developing Team Science as a new paradigm for psychiatric genomics and forging international collaborative efforts and consortia. He has also been instrumental in developing and consolidating genomics resources for the research community through participation in developing NIH data sharing policies for genomics including the Genomic Data Sharing (GDS) policy and its implementation.

Dr. Miller holds the A.W. and Mary Margaret Clausen Distinguished Professorship in Neurology at the University of California, San Francisco (UCSF). He directs the busy UCSF dementia center where patients in the San Francisco Bay Area and beyond receive comprehensive clinical evaluations. His goal is the delivery of model care to all of the patients who enter the clinical and research programs at the UCSF Memory and Aging Center (MAC).

Dr. Miller is a behavioral neurologist focused on dementia with special interests in brain and behavior relationships as well as the genetic and molecular underpinnings of disease. His work in frontotemporal dementia (FTD) emphasizes both the behavioral and emotional deficits that characterize these patients, while simultaneously noting the visual creativity that can emerge in the setting of FTD. He is the principal investigator of the NIH-sponsored Alzheimer’s Disease Research Center (ADRC) and program project on FTD called Frontotemporal Dementia: Genes, Imaging and Emotions. He oversees a healthy aging program, which includes an artist in residence program. In addition, he helps lead two philanthropy-funded research consortia, the Tau Consortium and Consortium for Frontotemporal Research, focused on developing treatments for tau and progranulin disorders, respectively. Also, he works with the National Football League to help with the education and assessment of players related to brain health. Dr. Miller teaches extensively, runs the Behavioral Neurology Fellowship at UCSF, and oversees visits of more than 50 foreign scholars every year.

Dr. Miller has received many awards including the Potamkin Award from the American Academy of Neurology, the Raymond Adams Lecture at the American Neurological Association, the Elliot Royer Award from the San Francisco Neurological community, the UCSF Annual Faculty Research Lectureship in Clinical Science, the UCSF Academic Senate Distinction in Mentoring Award, Distinguished Service to Minorities, from Charles Drew University, and the Gene D. Cohen Research Award in Creativity and Aging from the National Center for Creative Aging. He has authored The Human Frontal Lobes, The Behavioral Neurology of Dementia, Frontotemporal Dementia and over 600 other publications regarding dementia. He has been featured in Fortune magazine and The New York Times, as well as on "Charlie Rose," "PBS NewsHour" and other media. For more than three decades, Dr. Miller has been the scientific director for the philanthropic organization The John Douglas French Alzheimer’s Foundation, a private philanthropic organization that funds basic science research in Alzheimer’s disease.

Matthew W. State MD, PhD, is a child psychiatrist and human geneticist studying pediatric neuropsychiatric syndromes. His lab focuses on gene discovery as a launching point for efforts to illuminate the biology of these conditions and to develop novel and more effective therapies.

Dr. State received his undergraduate and medical degrees at Stanford University, completed his residency in psychiatry and fellowship in child psychiatry at the UCLA Neuropsychiatric Institute, and earned a PhD in genetics from Yale University. He was on the faculty at Yale from 2001 to 2013 where he was the Donald J. Cohen Professor of Child Psychiatry, Psychiatry and Genetics and the Co-Founder and Co-Director of the Yale Program on Neurogenetics. He is currently the Oberndorf Family Distinguished Professor and Chair of Psychiatry at UCSF and Director of the Langley Porter Psychiatric Institute and Hospital.

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.06.2016

Herausgeber

Verlag

Academic Press

Seitenzahl

796

Maße (L/B/H)

28,2/22/4,8 cm

Gewicht

2310 g

Sprache

Englisch

ISBN

978-0-12-800105-9

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Produktbild: Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Section 1 The Genome Tools and Methods

    1. The Newly Emerging View of the Genome

    Stephan Sanders

    2. Genetic Epidmeiology

    Kathleen Ries Merikangas

    3. Common Variation

    Mark Daly

    4. Rare/Structural Variation

    Daniel Barrera and Jonathan Sebat

    5. Epigenetics and Epigenomics

    Eric J. Nestler and John Greally

    6. Bioinformatics

    Shaun Purcell

    7. Imaging Genomics

    Paul Matthew Thompson

    8. Stem Cell Technology and Genomics

    Alysson Renato Muotri

    9. Association Strategies

    Benjamin M. Neale

    10. The promise of Systems Biology

    Eric Schadt

    11. Gene networks in neuropsychiatric disease

    Daniel Geschwind

    12. Mosaicism

    Christopher A. Walsh and Saumya Shekhar Jamuar

    Section 2 A new neuroanatomy

    13. Mapping the Molecular Landscape of the Human Brain

    Nenad Sestan

    14. Studying Circuits

    Stephan Lammel and Robert Malenka

    15. Electrophysiological Measurement of Circuits

    Srikantan S. Nagarajan

    16. Imaging the Circuitry of the Human Brain

    Michael Greicius

    17. Neuroimaging Advances in Alzheimer's Disease

    Daniel R. Schonhaut and Gil Rabinovici

    18. Progressive Supranuclear Palsy and Related Parkinsonian Disorders

    Jesse A. Brown and William Seeley

    19. The Anatomy of Basal Ganglia Circuitry of Behavior

    Nicholas Au Yong, Adrienne M. Keener, Yvette Bordelon, Carlos Portera-Cailliau and Nader Pouratian

    20. Brainstem Circuitry of Behavior

    Helmut Heisen

    21. Apathy - Basal Ganglia, Frontal Circuits

    Mario F. Mendez

    22. Emotion Circuitry

    Robert Wayne Levenson

    23. Delusions

    Georges Naasan

    24. Hallucinations

    Dennis Velakoulis

    Section 3 Clinical Phenomenology

    25. Intro: Risk Overlap Among Disorders

    Patrick Sullivan

    26. The conundrum of Clinical Characterization RDOC/ICD-10/DSM

    Bruce N. Cuthbert

    27. Schizophrenia

    Aiden Corvin

    28. Psychosis

    Raquel E. Gur and Ruben Gur

    29. ASD

    Rebecca Ann Muhle, Stephan Sanders, Hannah Reed and Matthew William State

    30. Bipolar Disorder

    Nelson B. Freimer, Carrie E. Bearden and Peter Zandi

    31. MDD

    David C. Glahn

    32. Speech and Language Disorders

    Marilu Gorno-Tempini

    33. Molecular Pathways Leading to the Clinical Phenomenology of Frontotemporal Dementia

    Suzee Eurie Lee and Jennifer S. Yokoyama

    34. Alzheimer's

    Rudy Tanzi

    35. PTSD

    Kerry Ressler

    36. Neurodevelopmental syndromes

    Elliott Sherr

    37. Epilepsies

    Ryan S. Dhindsa, Daniel Lowenstein and David Goldstein

    38. Substance Abuse

    Nii Addy

    39. Neuroimmunology

    Emmanuel Mignot

    40. Brain Tumors

    Vanessa Clark and Murat Günel

    41. White Matter Disorders

    Michael David Geschwind and Brianne Magouirk Bettcher

    42. ALS

    Elena Ratti and James Berry

    43. Eating Disorders

    Cynthia M. Bulik and Garret Stuber

    Section 4 Clinical Translation and Drug Development

    44. Pharmacogenomics

    Roy H. Perlis