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The Molecular Basis of Cancer

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Beschreibung

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding...

Beschreibung

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application.

  • Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer.
  • Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures.
  • Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy.
  • Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology.
  • Access the entire text and illustrations online, fully searchable, at Expert Consult.

Rezension

"This is a well-organized and well-written book that improves readers' understanding of the diverse mechanisms involved in cancer risk, growth, and treatments. The book provides a unique experience, uniting basic science with clinical applications to provide an integrated appreciation of the diverse molecular biology of cancer. It should be in the library of anyone interested in cancer research and treatment."-Karen L Reckamp, MD, MS(City of Hope) Doody Review: 4 stars

2015 BMA Medical Book Awards: Highly Commended in Oncology

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.02.2014

Verlag Elsevier LTD, Oxford
Seitenzahl

888

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.02.2014

Verlag Elsevier LTD, Oxford
Seitenzahl

888

Maße (B/H)

21,5/27,6 cm

Gewicht

1950 g

Auflage

4. Auflage

Sprache

Englisch

ISBN

978-1-4557-4066-6

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  • Produktbild: The Molecular Basis of Cancer
  • The Molecular Basis of Cancer, 4e

    Mendelsohn, Howley, Israel, Gray, Thompson

    Part I: Carcinogenesis and Cancer Genetics

    1. Cancer, A Genetic Disorder

    2. Oncogenes and Signal Transduction

    3. Tumor Suppressor Genes

    4. Genomic Instability and DNA Repair

    5. Epigenetics and Cancer

    6. Infectious Agents and Cancer

    7. Environmental Carcinogenesis

    8. Animal Models: Flies, Fish and Yeast

    9. Genetic Mouse Models of Cancer

    Part II: Cancer Biology

    10. Cancer Stem Cells

    11. Regulation of the Cell Cycle

    12. Cell Growth

    13. Cancer Cell Metabolism

    14. Apoptosis, Autophagy and Necrosis

    15. Cell Growth Arrest and Senescence

    16. Stromal-Cancer Interactions in the Microenvironment

    17. Hypoxia and Angiogenesis

    18. Invasion and Metastasis

    19. Inflammation and Cancer

    20. Molecular Pathways and Systems Biology

    Part III: Molecular Pathology and Diagnostics

    21. Biomarkers Assessing Risk of Cancer

    22. Biomarkers for Detecting Cancer: Molecular Screening

    23. Biomarkers for Predicting Response to Specific Therapy

    24. The Technology of Analyzing Nucleic Acids

    25. Imaging Cancer