Introduction: Genetic Constraints on Adaptive Evolution and the Evolution of Genetic Constraints.- 1 A Quantitative Genetic Perspective on Adaptive Evolution.- 2 Genetic Correlations: The Quantitative Genetics of Evolutionary Constraints.- 3 Genetic Constraints on the Evolution of Phenotypic Plasticity.- 4 Reflections on the Genetics of Quantitative Traits with Continuous Environmental Variation.- 5 Three Approaches to Trade-Offs in Life-History Evolution.- 6 Pleiotropy in Dynamical Parameters of Models on the Evolution of Simple Phenotypes.- 7 Constraints in Selection Response.- 8 Nonrandom Patterns of Mutation are Reflected in Evolutionary Divergence and May Cause Some of the Unusual Patterns Observed in Sequences.- 9 Genetic Constraints on Plant Adaptive Evolution.