Produktbild: The Handbook of Biomarkers

The Handbook of Biomarkers

175,99 €

inkl. gesetzl. MwSt.

Beschreibung

Produktdetails

Format

PDF

Kopierschutz

Nein

Family Sharing

Nein

Text-to-Speech

Nein

Erscheinungsdatum

06.02.2010

Verlag

Humana Press

Seitenzahl

492 (Printausgabe)

Dateigröße

3420 KB

Sprache

Englisch

EAN

9781607616856

Beschreibung

Rezension

ook fulfills the need for a single, comprehensive guide through the discovery, validation, and application of various biomarkers.” (Rachel Renee Chennault, Doody’s Review Service, July, 2010)

Zitat

From the reviews:
"Whilst reading the handbook, it is clear that it is understood what a biomarker is, the technologies used for assessment and at a glance which potential biomarkers are available for which disease state ... . Jain evaluates biomarker scaling from the cellular level to large size proteins through to nanoparticles for use in the clinic. ... this book is an excellent starting reference point for all of us scientists in many fields who need to know more." (Steve Crome and Kam Seehra, BTS Newsletter, Issue 37, Winter, 2010)
"This is a comprehensive overview of biomarkers characterized to date, technologies used in their identification, and the relevance of these biomarkers to clinical diagnostics as well as the drug discovery and development process. ... This will be an effective resource for individuals participating in both basic research and clinical applications relating to biomarkers, as well as those involved in drug discovery/development processes. ... This book fulfills the need for a single, comprehensive guide through the discovery, validation, and application of various biomarkers." (Rachel Renee Chennault, Doody's Review Service, July, 2010)

Produktdetails

Format

PDF

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Kopierschutz

Nein

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Text-to-Speech

Nein

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Barrierefreiheit

  • keine Information zur Barrierefreiheit bekannt

Erscheinungsdatum

06.02.2010

Verlag

Humana Press

Seitenzahl

492 (Printausgabe)

Dateigröße

3420 KB

Sprache

Englisch

EAN

9781607616856

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  • Produktbild: The Handbook of Biomarkers
  • 1. Introduction -Definitions
    -Historical aspects of biomarkers
    -Classification of biomarkers
    -Types of biomarkers
    -The ideal biomarker -Biomarkers and systems biology
    -Relation of biomarkers to other technologies and healthcare 2. Technologies for Discovery of Biomarkers
    -Introduction
    -Detection of biomarkers in tissues and body fluids
    -Disease biomarkers in breath
    -Genomic technologies
    -Epigenomic technologies -Proteomic technologies -Glycomic technologies
    -Metabolomic technologies
    -Lipidomics -Fluorescent indicators for biomarkers
    -Molecular imaging technologies
    -Nuclear magnetic resonance
    -Nanobiotechnology -Bioinformatics -Pitfalls in the discovery and development of biomarkers
    3. Biomarkers and Molecular Diagnostics -Introduction
    -Molecular diagnostic technologies -Detection and expression profiling of miRNA 4. Biomarkers for Drug Discovery & Development -Introduction
    -Biomarker technologies for drug discovery
    -Biomarkers and drug safety
    -Applications of biomarkers for drug development
    5. Role of Biomarkers in Healthcare
    -Introduction -Biomarkers of inflammation
    -Biomarkers of oxidative stress
    -Biomarkers in metabolic disorders
    -Biomarkers in immune disorders
    -Biomarkers of musculoskeletal disorders
    -Biomarkers of osteoporosis
    -Biomarkers of infectious diseases -Biomarkers of liver disease
    -Biomarkers of pancreatitis -Biomarkers of renal disease
    -Biomarkers of pulmonary diseases
    -Biomarkers in obstetrics and gynecology
    -Biomarkers for genetic disorders
    -Biomarkers of aging
    -Biomarkers of miscellaneous disorders -Biomarkers and nutrition -Biomarkers of gene-environmental interactions in human disease -Future role of biomarkers in healthcare
    -Applications of biomarkers beyond healthcare 6. Biomarkers of Cancer
    -Introduction
    -Types of cancer biomarkers -Molecular diagnostic techniques for cancer -Technologies for detection of cancer biomarkers
    -Applications of cancer biomarkers
    -Role of biomarkers in drug development in oncology
    -Biomarkers according to location/type of cancer
    -Role of the NCI in biomarkers of cancer
    -Future prospects for cancer biomarkers 7. Biomarkers of Disorders of the Nervous System
    -Introduction
    -Discovery of biomarkers for neurological disorders
    -Data mining for biomarkers of neurological disorders -Antibodies as biomarkers in disorders of the nervous system
    -Biomarkers of neural regeneration -Biomarkers of disruption of blood-brain barrier
    -Biomarkers of neurotoxicity
    -Biomarkers of neurodegenerative disorders
    -Biomarkers of multiple sclerosis
    -Biomarkers of stroke
    -Biomarkers of traumatic brain injury -Biomarkers of CNS infections
    -Biomarkers of epilepsy
    -Biomarkers of normal pressure hydrocephalus
    -Biomarkers of retinal disorders
    -Biomarkers for autism
    -Biomarkers of sleep disorders
    -Biomarkers of psychiatric disorders 8. Biomarkers of Cardiovascular Disorders
    -Introduction
    -Biomarkers of cardiovascular diseases -Methods for identification of cardiovascular biomarkers
    -Applications of biomarkers of cardiovascular disease
    -Role of biomarkers in the management of cardiovascular disease -Future prospects for cardiovascular biomarkers
    9. Biomarkers & Personalized Medicine
    -Introduction -Pharmacogenetics
    -Pharmacogenomics
    -Pharmacoproteomics
    -Role of biomarkers in development of personalized drugs
    -Biobanking, biomarkers and personalized medicine in EU
    -Expression signatures as diagnostic/prognostic tools
    -Biomarkers for monitoring response to therapy -Drug rescue by biomarker-based personalized medicine
    -Future role of biomarkers in personalized medicine
    10. Regulatory issues
    -Introduction
    -Biomarker validation
    -FDA perspective of biomarkers in clinical trials
    -FDA and predictive medicine
    -Biomarkers and FDA's Voluntary Genomic Data Submission
    -Role of imaging biomarkers in approval of drugs
    -FDA Critical Path Initiative and biomarker R&D