• Produktbild: Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes
  • Produktbild: Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes
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Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

08.10.2012

Abbildungen

VIII, 294 p.

Herausgeber

Emel Arinç + weitere

Verlag

Springer Us

Seitenzahl

294

Maße (L/B/H)

25,4/17,8/1,7 cm

Gewicht

583 g

Auflage

Softcover reprint of the original 1st ed. 1999

Sprache

Englisch

ISBN

978-1-4613-7202-8

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

08.10.2012

Abbildungen

VIII, 294 p.

Herausgeber

Verlag

Springer Us

Seitenzahl

294

Maße (L/B/H)

25,4/17,8/1,7 cm

Gewicht

583 g

Auflage

Softcover reprint of the original 1st ed. 1999

Sprache

Englisch

ISBN

978-1-4613-7202-8

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes
  • Produktbild: Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes
  • 1. The Fate of Xenobiotics in the Body: Enzymes of Metabolism.- 2. Protein-Protein Interactions in the P450 Monooxygenase System.- 3. Structures of Mitochondrial P450 System Proteins.- 4. Biochemical Aspects of Flavin-Containing Monooxygenases (FMOs).- 5. Expression and Regulation of Flavin-Containing Monooxygenases.- 6. Correlations between in Vivo and in Vitro Studies in Human Drug Metabolism.- 7. Pharmacogenetics: Polymorphisms in Xenobiotic Metabolism.- 8. Clinical Aspects of Polymorphic Drug Metabolism in Humans.- 9. Genetic Polymorphisms of Cytochromes P450 1 A1 and 2E1 and of Glutathione S-Transferase M1 and Cancer Susceptibility in the Human.- 10. Cytochrome P450 Isoforms: Insecticide Metabolism in Insects and Mammals and Role in Insecticide Resistance.- 11. Inhibitors of CYP51 as Antifungal Agents and Resistance to Azole Antifungals.- 12. The Role of Oxidative Drug Metabolizing Enzymes in Liver and Lung Specific Toxicity.- 13. Importance of Drug Metabolism in Drug Discovery and Development.- 14. Aflatoxin Biotransformation and Toxicology.- 15. Role of Individual Enzymes in the Control of Genotoxic Metabolites.- 16. Enhancement of the Mutagenicity of Ethylene Oxide and Several Directly Acting Mutagens by Human Erythrocytes and Its Reduction by Xenobiotic Interaction.- 17. Cytochrome P4501 Al (Cyp 1A1) and Associated MFO Activities in Fish as an Indicator of Pollution with Special Reference to Izmir Bay.- 18. Cyp 1A Concentrations as an Indicator of Exposure of Fish to Pulp-Mill Effluents.- 19. The Biochemistry and Physiology of Prostacyclin- and Thromboxane-Synthase.- 20. Cell Engineering of the Rat and Human Cysteine Conjugate Beta Lyase Genes and Applications to Nephrotoxicity Assessment.