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Produktbild: Solid-State Properties of Pharmaceutical Materials
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Solid-State Properties of Pharmaceutical Materials

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

28.08.2017

Verlag

John Wiley & Sons

Seitenzahl

432

Maße (L/B/H)

28,6/22,1/2,7 cm

Gewicht

1318 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-1-118-14530-2

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

28.08.2017

Verlag

John Wiley & Sons

Seitenzahl

432

Maße (L/B/H)

28,6/22,1/2,7 cm

Gewicht

1318 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-1-118-14530-2

EU-Ansprechpartner

Zeitfracht Medien GmbH
Ferdinand-Jühlke-Straße 7
99095 Erfurt
DE
produktsicherheit@zeitfracht.de

Herstelleradresse

Wiley & Sons
1 Oldlands Way
PO22 9NQ Bognor Regis
GB
trade@wiley.com

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  • Produktbild: Solid-State Properties of Pharmaceutical Materials
  • Preface
     
    Acknowledgments
     
    Chapter 1: Solid State Properties and Pharmaceutical Development
     
    1.1 Introduction
     
    1.2 Solid State Forms
     
    1.3 ICH Q6A Decision Trees
     
    1.4 "Big Questions" for Drug Development
     
    1.5 Accelerating Drug Development
     
    1.6 Solid State Chemistry in Preformulation and Formulation
     
    1.7 Learning before Doing and Quality by Design
     
    1.8 Performance and Stability in Pharmaceutical Development
     
    1.9 Moisture Uptake
     
    1.10 Solid State Reactions
     
    1.11 Noninteracting Formulations - Physical Characterizations
     
    References
     
    Chapter 2: Polymorphs
     
    2.1 Introduction
     
    2.2 How Are Polymorphs Formed?
     
    2.3 Structural Aspect of Polymorphs
     
    2.4 Physical, Chemical, and Mechanical Properties
     
    2.5 Thermodynamic Stability of Polymorphs
     
    2.6 Polymorph Cconversion
     
    2.7 Control of Polymorphs
     
    2.8 Polymorph Screening
     
    2.9 Polymorph Prediction
     
    References
     
    Chapter 3: Solvates and Hhydrates
     
    3.1 Introduction
     
    3.2 Pharmaceutical Importance of Hydrates
     
    3.3 Classification of Pharmaceutical Hydrates
     
    3.4 Water Aactivity
     
    3.5 Stoichiometric Hhydrates
     
    3.6 Nonstoichiometric Hhydrates
     
    3.7 Hydration/Dehydration
     
    3.8 Preparation and Characterization of Hydrates and Solvates
     
    References
     
    Chapter 4: Pharmaceutical Salts
     
    4.1 Introduction
     
    4.2 Importance of Pharmaceutical Salts
     
    4.3 Weak Acid, Weak Base, and Salt
     
    4.4 pH-Solubility Profiles of Ionizable Compounds
     
    4.5 Solubility, Dissolution and Bioavailability of Pharmaceutical Salts
     
    4.6 Physical Stability of Pharmaceutical Salts
     
    4.7 Strategies for S salt Sselection
     
    References
     
    Chapter 5: Pharmaceutical Co-crystals
     
    5.1 Introduction
     
    5.2 Co-crystals and Crystal Engineering
     
    5.3 Co-crystals and Crystal Engineering
     
    5.4 Co-crystals and Crystal Engineering
     
    5.5 Solubility Phase Diagrams for Co-crystals
     
    5.6 Preparation of Co-crystals
     
    5.7 Dissolution and Bioavailability of Co-crystals
     
    5.8 Comparison of Ppharmaceutical Ssalts and Cco-crystals
     
    References
     
    Chapter 6: Amorphous Solids
     
    6.1 Introduction
     
    6.2 The Formation of Amorphous Solids
     
    6.3 Methods of Preparing Amorphous Solids
     
    6.4 The Glass Transition Temperature
     
    6.5 Structural Features of Amorphous Solids
     
    6.6 Molecular Mobility
     
    6.7 Mixtures of Amorphous Solids
     
    6.8 References
     
    Chapter 7: Crystal Mesophases and Nanocrystals
     
    7.1 Introduction
     
    7.2 Overview of Crystal Mesophases
     
    7.3 Liquid Crystals
     
    7.4 Conformationally Disordered (Condis) Crystals
     
    7.5 Plastic Crystals
     
    7.6 Nanocrystals
     
    References
     
    Chapter 8: X-ray Crystallography and Crystal Packing Analysis
     
    8.1 Introduction
     
    8.2 Crystals
     
    8.3 Miller Indices and Crystal Faces
     
    8.4 Determination of the Miller Indices of the Faces of a Crystal
     
    8.5 Determination of Crystal Structure
     
    References
     
    Chapter 9: X-ray Crystallography and Crystal Packing Analysis X-ray Powder Diffraction
     
    9.1 Introduction
     
    9.2 X-ray Powder Diffraction of Crystalline Materials
     
    9.3 Qualitative Analysis of Crystalline Materials
     
    9.4 Phase Transformations
     
    9.5 Quantitative Phase Analysis Using XRPD
     
    9.6 Solving Crystal