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Cytochrome P450 Protocols

Aus der Reihe Methods in Molecular Biology
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142,99 € UVP 164,99 €

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

09.03.2013

Herausgeber

Ian R. Phillips + weitere

Verlag

Humana Press

Seitenzahl

319

Maße (L/B/H)

26/18,3/2,3 cm

Gewicht

7684 g

Auflage

3rd edition 2013

Sprache

Englisch

ISBN

978-1-62703-320-6

Beschreibung

Rezension

From the reviews of the third edition:

“With this third edition, the authors and contributors continue to provide what has become a tour de force of bench top manuals for the cytochrome P450 field. … this book should also prove of interest to graduate students and postdoctoral researchers who are new to the field of P450 science, or who would like to expand their research directions. … This stands alone as the premier book for this field, which is sorely lacking in publications of this type.” (Jed N. Lampe, Doody’s Book Reviews, October, 2013)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

09.03.2013

Herausgeber

Verlag

Humana Press

Seitenzahl

319

Maße (L/B/H)

26/18,3/2,3 cm

Gewicht

7684 g

Auflage

3rd edition 2013

Sprache

Englisch

ISBN

978-1-62703-320-6

Herstelleradresse

Springer-Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

Email: GPSR Kontakt

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  • Produktbild: Cytochrome P450 Protocols
  • Produktbild: Cytochrome P450 Protocols
  • 1. Bioluminescent Assays for Cytochrome P450 Enzymes
                Douglas S. Auld, Henrike Veith, and James J. Cali
     
    2. In Vitro Drug-Drug Interaction Assay      
                Michael Zientek and Kuresh Youdim
     
    3. High-Throughput Mass Spectrometric Cytochrome P450 Inhibition Screening
                Kheng B. Lim, Can C. Ozbal, and Daniel B. Kassel
     
    4. The Synthesis, Characterization and Application of 13C-Methyl Isocyanide as an NMR Probe of Heme Protein Active Sites
                Christopher McCullough, Phani Kumar Pullela, Sang-Choul Im, Lucy Waskell, Daniel Sem
     
    5. High-Throughput Fluorescence Assay for Cytochrome P450 Mechanism-Based Inactivators    
                Cesar Kenaan, Haoming Zhang, and Paul F. Hollenberg
     
    6. Identification of Endogenous Substrates of Orphan Cytochrome P450 Enzymes Through the Use of Untargeted Metabolomics Approaches
                Qian Cheng and F. Peter. Guengerich
     
    7. Genetic and Mass Spectrometric Tools for Elucidating the Physiological Function(s) of Cytochrome P450 Enzymes from Mycobacterium Tuberculosis
                Hugues Ouellet, Eric D. Chow, Shenheng Guan, Jeffery S. Cox, Alma L. Burlingame, and Paul R. Ortiz de Montellano
     
    8. An Escherichia coli Expression-Based Approach for Porphyrin Substitution in Heme Proteins  
                Michael B. Winter, Joshua J. Woodward, and Michael A. Marletta
     
    9. Expression in Escherichia coli of a Cytochrome P450 Enzyme with a Cobalt Protoporphyrin IX Prosthetic Group
                Wesley E. Straub, Clinton R. Nishida, and Paul R. Ortiz de Montellano
     
    10. Nanodiscs in the Studies of Membrane-Bound Cytochrome P450 Enzymes     
                A. Luthra, M. Gregory, Y.V. Grinkova, I.G. Denisov , and S.G. Sligar
     
    11. Rapid LC-MS Drug Metabolite Profiling Using Bioreactor Particles
                Linlin Zhao, Besnik Bajrami, and James F. Rusling
     
    12. Fluorescence-Based Screening of cytochrome P450 activities in Intact Cells
                M. Teresa Donato and M. José Gómez-Lechón
     
    13. Screening for Cytochrome P450 Reactivity with a Reporter Enzyme
                Kersten S. Rabe and Christof M. Niemeyer
     
    14. High-Throughput Fluorescence Assay of Cytochrome P450 3A4          
                Qian Cheng and F. Peter. Guengerich
     
    15. Targeted Protein Capture for Analysis of Electrophile-Protein Adducts
                Rebecca E. Connor, Simona G. Codreanu, Lawrence J. Marnett, and Daniel C. Liebler
     
    16. DNA Shuffling of Cytochrome P450 Enzymes
                James B.Y.H. Behrendorff, Wayne A. Johnston, and Elizabeth M.J. Gillam
     
    17. Measurement of P450 Difference Spectra Using Intact Cells
                Wayne A. Johnston and Elizabeth M.J. Gillam
     
    18. DNA Shuffling of Cytochromes P450 for Indigoid Pigment Production
                Nedeljka N. Rosic
     
    19. P450 oxidoreductase – Genotyping, Expression, Purification of Recombinant Protein and Activity Assessments of Wild-Type and Mutant Protein
                Vishal Agrawal and Walter L. Miller
     
    20. LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochromes P450
                Federico Sabbadin, Gideon G. Grogan and Neil C. Bruce
     
    21. Update on Allele Nomenclature for Human Cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database
                Sarah C. Sim and Magnus Ingelman-Sundberg
     
    22. Simultaneous in vivo Phenotyping of CYP Enzymes
                Sussan Ghassabian and Michael Murray
     
    23. Detection of Regulatory Polymorphisms: High-Throughput Capillary DNase-I Footprinting
                Matthew Hancock and Elizabeth A. Shephard
     
    24. Isolation of Mouse Hepatocytes
                Mina Edwards, Lyndsey Houseman, Ian R. Phillips, and Elizabeth A. Shephard 
    25. Highly Efficient SiRNA and Gene Transfer into Hepatocyte-like HepaRG Cells and Primary Human Hepatocytes: New Means for Drug Metabolism and Toxicity Studies
                Véronique Laurent, Denise Glaise, Tobias Nübel, David Gilot, Anne Corlu, and Pascal Loyer