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  • Produktbild: Concepts in Biochemical Pharmacology
  • Produktbild: Concepts in Biochemical Pharmacology
Band 28

Concepts in Biochemical Pharmacology Part 2

Aus der Reihe Handbook of Experimental Pharmacology

99,99 €

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

30.01.2012

Abbildungen

XX, 778 p.

Herausgeber

Bernard B. Brodie + weitere

Verlag

Springer Berlin

Seitenzahl

778

Maße (L/B/H)

24,4/17/4,3 cm

Gewicht

1360 g

Auflage

Softcover reprint of the original 1st ed. 1971

Sprache

Englisch

ISBN

978-3-642-65179-3

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

30.01.2012

Abbildungen

XX, 778 p.

Herausgeber

Verlag

Springer Berlin

Seitenzahl

778

Maße (L/B/H)

24,4/17/4,3 cm

Gewicht

1360 g

Auflage

Softcover reprint of the original 1st ed. 1971

Sprache

Englisch

ISBN

978-3-642-65179-3

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: Concepts in Biochemical Pharmacology
  • Produktbild: Concepts in Biochemical Pharmacology
  • Section Four: Methods of Studying the Metabolism of Drugs.- Subsection A. Assay of Drugs and Their Metabolites.- 22: Basic Principles in Development of Methods for Drug Assay. With 2 Figures.- 23: Absorption Spectrophotometry.- 24: Fluorometry. With 1 Figure.- 25: Radioactive Techniques: The Use of Labeled Drugs. With 2 Figures.- 26: Radioactive Techniques: Radioactive Isotope Derivatives of Nonlabeled Drugs.- 27: Gas Chromatography. With 18 Figures.- 28: Enzymatic Assays in Pharmacology. With 4 Figures.- 29: Bioassay. With 2 Figures.- 30: Immunoassay. With 2 Figures.- Subsection B. Isolation and Identification of Drug Metabolites.- 31: Paper, Column and Thin Layer Chromatography, Counter-Current Distribution and Electrophoresis..- 32: Isotope Dilution Analysis. With 4 Figures.- 33: Gas Chromatography-Mass Spectrometry. With 8 Figures.- 34: The Application of Various Spectroscopies to the Identification of Drug Metabolites. With 5 Figures.- Section Five: Sites of Drug Metabolism.- 35: Introduction: Pathways of Drug Metabolism.- Subsection A: Microsomal Enzymes.- 36: Some Morphological Characteristics of Hepatocyte Endoplasmic Reticulum and Some Relationships between Endoplasmic Reticulum, Microsomes, and Drug Metabolism.- 37: Model Systems in Studies of the Chemistry and the Enzymatic Activation of Oxygen. With 9 Figures.- 38: Cytochrome P-450 — Its Function in the Oxidative Metabolism of Drugs. With 23 Figures.- 39: Enzymatic Oxidation at Carbon.- 40: N-Oxidation Enzymes. With 2 Figures.- 41: Enzymatic N-, 0-, and S-Dealkylation of Foreign Compounds by Hepatic Microsomes. With 4 Figures.- 42: Reductive Enzymes. With 6 Figures.- 43: Oxidative Desulfuration and Dearylation of Selected Organophosphate Insecticides.- 44: Metabolism of Halogenated Compounds. With 7Figures.- 45: Glucuronide-Forming Enzymes. With 1 Figure.- 46: Metabolism of Normal Body Constituents by Drug-Metabolizing Enzymes in Liver Microsomes.- 47: Tissue Distribution Studies of Polycyclic Hydrocarbon Hydroxylase Activity.- 48: Mechanisms of Induction of Drug Metabolism Enzymes. With 9 Figures.- 49: Inhibition of Drug Metabolism. With 1 Figure.- Subsection B: Nonmicrosomal Enzymes.- 50: Esterases of Human Tissues. With 2 Figures.- 51: Enzymatic Oxidation and Reduction of Alcohols, Aldehydes and Ketones.- 52: Amine Oxidases.- 53: Sulphate Conjugation Enzymes. With 3 Figures.- 54: Acetylating, Deacetylating and Amino Acid Conjugating Enzymes. With 3 Figures.- 55: Mercapturic Acid Conjugation. With 1 Figure.- 56: Methyltransferase Enzymes in the Metabolism of Physiologically Active Compounds and Drugs.- 57: Enzymes that Inactivate Vasoactive Peptides. With 2 Figures.- 58: The Metabolism of Analogs of Endogenous Substrates: Wider Application of a Limited Concept. With 15 Figures.- Author Index.