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Produktbild: Effects of Mineral Dusts on Cells
Band 30

Effects of Mineral Dusts on Cells

Aus der Reihe Nato ASI Subseries H:

99,99 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

23.12.2011

Herausgeber

Brooke T. Mossman + weitere

Verlag

Springer Berlin

Seitenzahl

470

Maße (L/B/H)

24,2/17/2,7 cm

Gewicht

827 g

Auflage

Softcover reprint of the original 1st ed. 1989

Sprache

Englisch

ISBN

978-3-642-74205-7

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

23.12.2011

Herausgeber

Verlag

Springer Berlin

Seitenzahl

470

Maße (L/B/H)

24,2/17/2,7 cm

Gewicht

827 g

Auflage

Softcover reprint of the original 1st ed. 1989

Sprache

Englisch

ISBN

978-3-642-74205-7

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: GPSR Kontakt

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  • Produktbild: Effects of Mineral Dusts on Cells
  • A. Epithelial Cell Injury and Proliferation by Minerals.- 1. Effects of Cigarette Smoke on Uptake of Asbestos and Iron Oxide by Rat Tracheal Explants.- 2. Cytotoxicity of Asbestos and Calcium-Silicates to Various Lung Epithelial Cell Types InVitro.- 3. Injurious Effects of Mineral Dust-Elicited Bronchoalveolar Leukocytes on Epithelial Cells InVitro: The Role of Extracellular Matrix Components.- B. Physico-Chemical Properties of Minerals in Relation to their Biologic Effects.- 1. Toxicity of Chrysotile Asbestos through Surface Modification with Chelating Agents.- 2. A Comparison of the In Vitro and In Vivo Toxicity of Fibrous and Non-Fibrous Silicon Nitride.- 3. Membranolytic Activity and Morphological Characterization of Palygorskite and Sepiolite.- 4. Mineral Surface-Specific Differences in the Adsorption and Enzymatic Removal of Surfactant and their Correlation with Cytotoxicity.- C. Mechanisms of Dust-Induced Pneumoconioses. Clinical and Experimental Studies.- 1. Bronchoalveolar Lavage Cells in Occupational Exposure to Mineral Fibers.- 2. Alveolar Macrophages Secretory Dysfunctions in Coal Worker’s Pneumoconiosis. Comparison Between Simple Pneumoconiosis and Progressive Massive Fibrosis.- 3. Cellularity in Bronchoalveolar Lavage in Cement Dust Aggression.- 4. Carborundum Pneumoconiosis.- D. Mechanisms of Cytotoxicity, Mutagenicity and Carcinogenicity.- 1. Influence of Physicochemical Properties of Beryllium and Nickel Compounds on Cultured Cell Toxicity.- 2. Comparative Study of the Effect of Various Fibres on the Secretion of Plasminogen Activator by Murine Peritoneal Macrophages.- 3. Release of Interleukin-1 and Tumor Necrosis Factor by Rat Alveolar Macrophages after InVivo or InVitro Exposure to Mineral Dusts.- 4. The Effect of Aramid and Metaphosphate Fibers on Macrophage Viability and Function.- 5. Effects of Nicotinamide on the Cytotoxicity of Mineral Dusts towards Pulmonary Alveolar Macrophages.- 6. Long-Term Effect of 3Methylcholanthrene-Coated Asbestos Fibres on the Immune Status of F1 (NZB*C57B1/6) Mice.- 7. Production of Growth Factors by Rat Pleural Mesothelial Cells InVivo or InVitro Transformed by Chrysotile Fibers.- 8. Mutagenicity of Asbestos and Erionite in a Salmonella Tester Strain of TA102.- 9. Induction of Sister Chromatid Exchanges by Fibrous Dusts Alone and in Combination with Other Xenobiotics in Chinese Hamster Cells.- 10. Pleural and Parenchymal Responses in Rats to Short-Term Inhalation Exposures to Erionite, Crocidolite, Chrysotile, Silica and Titanium Dioxide.- 11. InVitro Responses of Canine Alveolar Lymphocytes to BeSO4 After Inhalation Exposure to BeO.- E. Oxidants, Cytotoxicity and Disease.- 1. Oxidants, Antioxidants and Monokines in the Pathogenesis of Coal Workers’ Pneumoconiosis. Tumor Necrosis Factor as a Mediator in Lung Fibrosis.- 2. Use of Chemiluminescence Assays to Monitor the Surface Characteristics and Biological Reactivity of Freshly Fractured vs Aged Silica.- 3. Production of Free Radicals by Non-Fibrous Materials in a Cell-Free Buffer Medium.- 4. Detoxified Crocidolite Exhibits Reduced Radical Generation which Could Explain its Lower Toxicity: ESR and Mossbauer Studies.- 5. The Formation of Oxygen Reactive Radicals at the Surface of Crushed Quartz Dusts as a Possible Cause of Silica Pathogenicity.- 6. Arachidonic Acid Metabolite Production by Alveolar Macrophages Cultured in Gazeous Phase. Effects of NO2 and Diesel Exhaust.- 7. Superoxide Anion Production Induced by Chrysotile Asbestos in the Guinea Pig Alveolar Macrophage.- 8. Altered Calcium Homeostasis and Mineral Dust Toxicity.- 9. Formation of 8-Hydroxy-deoxyguanosine in DNA by MMMF.- 10. Effect of Chrysotile, Amosite and Crocidolite on the Oxidative Burst of Rabbit Alveolar Macrophages.- 11. Production of Radicals Arising from Surface Activity of Fibrous Minerals.- 12. Potential Role of Silicon-Oxygen Radicals in Acute Lung Injury.- 13. Oxygenated Radical Formation by Fresh Quartz Dust in a Cell-Free Aqueous Medium and its Inhibition by Scavengers.- F. Mechanisms of Mineral-Induced Inflammation.- 1. Interaction of Quartz with Bovine Alveolar Macrophages: Studies on Cytotoxicity, Electrophoretic Mobility and Subcellular Components.- 2. Degradation of an Extracellular Matrix Component by Broncho-alveolar. Leukocytes InVitro: Modulation by Mineral Dusts.- 3. Silica Induced Alveolar Leucocytosis: Modulation by Mepacrine.- 4. Altered Functional Expression of Alveolar Macrophage Subpopulations after Serpentine and Amphibole Asbestos Exposure.- 5. Particle Induced InVitro Chemotaxis of Alveolar Macrophages (AM) and Neutrophils and InVivo Effects.- 6. Consequences of MMMF Inhalation on Lung and Pleural Cavity Cell Populations.- 7. The Role of Alveolar Macrophage Activation in the Response to Mineral Fibers.- 8. InVitro Studies of Leukocytes Lavaged from the Lungs of Rats Following the Inhalation of Mineral Dusts.- 9. Predictive Value of InVitro Pulmonary Macrophage Functional Assays to Assess InVivo Clearance of Inhaled Particles.- 10. Leukotriene B4 and Tumor Necrosis Factor Production after InVitro Exposure of Rat Alveolar Macrophages to Mineral Dust: Potential Role in Fibrogenesis.- 11. Modulation of Macrophage-Mediated Cytotoxicity by Toxic Particles.- G. Mechanisms of Carcinogenesis.- 1. Effects of Asbestos Fibres on Some Aspects of the Cell Second Messenger System.- 2. A Model for the Influence of Inhaled Mineral Fibers on the Cellular Burden of Polycyclic Aromatic Hydrocarbons in the Lung.- 3. Oncogenic Transformation by Asbestos Fibers and Radon-Stimulated Alpha Particles.- 4. Studies on Cell Cycle of Rat Pleural Mesothelial Cells Submitted to Direct or Indirect Hit by Chrysotile Fibres.- 5. Effects of 3Methylcholanthrene-coated Asbestos on Hematological Status of F1 (NZB*C57B1/6) Mice.- 6. Occurrence and Morphology of Tumors Induced in Nude Mice Transplanted with Pleural Mesothelial Cells InVitro Treated with Chrysotile Fibres or Benzo 3-4 Pyrene.- 7. Cytotoxic, Hemolytic and Mutagenic Issue Caused by Chrysotile-Asbestos InVitro.- 8. Effects of Asbestos on Specific Binding of Phorbol Ester Tumor Promoter and Protein Kinase C Activity in Hamster Tracheal Epithelial (HTE) Cells.- H. Questions, Risks and Public Policy.- 1. Questions to the Cell Biologists and Proposals for a Definition and Classification of Carcinogenic Fibers Derived from Animal Studies.- 2. Risk Factors of Asbestos-Related Cancers.- 3. Mesothelioma Threshold.- I. Summary and Closing Remarks.