List of Contributors xi
 
Foreword xiii
 
Preface xv
 
1 Metalloproteins and Metallopeptides - Natural Metallofoldamers 1
Vasiliki Lykourinou and Li-June Ming
 
1.1 Introduction 1
 
1.2 Metalloproteins 2
 
1.3 Metallopeptides 12
 
1.4 Conclusion and Perspectives 28
 
Acknowledgements 30
 
References 30
 
2 Introduction to Unnatural Foldamers 51
Claudia Tomasini and Nicola Castellucci
 
2.1 General Definition of Foldamers 51
 
2.2 Biotic Foldamers 53
 
2.3 Abiotic Foldamers 70
 
2.4 Organization Induced by External Agents 72
 
2.5 Applications 78
 
2.6 Conclusions and Outlook 81
 
References 81
 
3 Self-Assembly Principles of Helicates 91
Josef Hamacek
 
3.1 Introduction 91
 
3.2 Thermodynamic Considerations in Self-Assembly 93

3.3 Cooperativity in Self-Assembly 100
 
3.4 Kinetic Aspects of Multicomponent Organization 104
 
3.5 Understanding Self-Assembly Processes 108
 
3.6 Secondary Structure and Stabilizing Interactions 118
 
3.7 Conclusions 118
 
References 120
 
4 Structural Aspects of Helicates 125
Martin Berg and Arne Lützen
 
4.1 Introduction 125
 
4.2 Structural Dynamics 127
 
4.3 Template Effects 129
 
4.4 Sequence Selectivity 130
 
4.5 Self-Sorting Effects in Helicate Formation 135
 
4.6 Diastereoselectivity I - "Meso"-Helicate versus Helicate Formation 138
 
4.7 Diastereoselectivity II - Enantiomerically Pure Helicates from Chiral Ligands 139
 
4.8 Summary and Outlook 150
 
References 151
 
5 Helical Structures Featuring Thiolato Donors 159
F. Ekkehardt Hahn and Dennis Lewing
 
5.1 Introduction 159
 
5.2 Coordination Chemistry of Bis- and Tris(Benzene-o-Dithiolato) Ligands 162
 
5.3 Coordination Chemistry of Mixed Bis(Benzene-o-Dithiol)/Catechol Ligands 176
 
5.4 Subcomponent Self-Assembly Reactions 181
 
5.5 Summary and Outlook 186
 
References 186
 
6 Photophysical Properties and Applications of Lanthanoid Helicates 193
Jean-Claude G. Bünzli
 
List of Acronyms and Abbreviations 193
 
6.1 Introduction 194
 
6.2 Homometallic Lanthanoid Helicates 197
 
6.3 Heterometallic d-f Helicates 223
 
6.4 Chiral Helicates 236
 
6.5 Extended Helical Structures 239
 
6.6 Perspectives 240
 
Acknowledgements 241
 
References 241
 
7 Design of Supramolecular Materials: Liquid-Crystalline Helicates 249
Raymond Ziessel
 
7.1 Introduction 249
 
7.2 Imino-Bipyridine and Imino-Phenanthroline Helicates 252
 
7.2.1 Liquid Crystals from Imino-Polypyridine Based Helicates 257
 
7.3 Conclusions 266
 
7.4 Outlook and Perspectives 267
 
Acknowledgements 268
 
References 268
 
8 Helicates, Peptide-Helicates and Metal-Assisted Stabilization of Peptide Microstructures 275
Markus Albrecht
 
8.1 Introduction 275
 
8.2 Selected Examples of Metal Peptide Conjugates 276
 
8.3 Helicates and Peptide-Helicates 279

8.4 Metal-Assisted Stabilization of Peptide Microstructures 288
 
8.5 Conclusion 298
 
References 300
 
9 Artificial DNA Directed toward Synthetic Metallofoldamers 303
Guido H. Clever and Mitsuhiko Shionoya
 
9.1 Introduction 303
 
9.2 The Quest for Alternative Base Pairing Systems 309
 
9.3 Design and Synthesis of Metal Base Pairs 311
 
9.4 Assembly and Analysis of Metal Base Pairs Inside the DNA Double Helix 315
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