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Produktbild: Cancer Drug Resistance
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Cancer Drug Resistance

Aus der Reihe Cancer Drug Discovery and Development
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215,99 € UVP 241,99 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

09.12.2010

Herausgeber

Beverly A. Teicher

Verlag

Humana Press

Seitenzahl

617

Maße (L/B/H)

25,4/17,8/3,4 cm

Gewicht

1177 g

Auflage

Softcover reprint of hardcover 1st ed. 2006

Sprache

Englisch

ISBN

978-1-61737-622-1

Beschreibung

Rezension

"...a resource to scientists of diverse specialties with interests relating to the repsonse of malignant disease to current and experimental therapies." - Neoplasma


"...an excellent book that is appropriate for scientists and clinicians with an interest in the basis of anticancer drug resistance." -Doody's Book Review, Weighted Numberical Score: 90 - 4 Stars!

Portrait

Cancer Drug Resistance represents a point on the path of the long journey toward understanding the complex interactions between host, tumor and cytotoxic or immunomodulatory agents. It addresses the resistance of solid tumors to anticancer therapeutics by considering mechanisms that involve alterations in genetics and epigenetics, cellular biochemistry, properties related to physiology of the solid tumor mass and alterations in host metabolic and immune status induced by the presence of malignant disease.

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

09.12.2010

Herausgeber

Beverly A. Teicher

Verlag

Humana Press

Seitenzahl

617

Maße (L/B/H)

25,4/17,8/3,4 cm

Gewicht

1177 g

Auflage

Softcover reprint of hardcover 1st ed. 2006

Sprache

Englisch

ISBN

978-1-61737-622-1

Herstelleradresse

Springer-Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

Email: ProductSafety@springernature.com

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  • Produktbild: Cancer Drug Resistance
  • Part I. Physiological Resistance

    The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumors
    Mark W. Dewhirst, Yiting Cao, Benjamin Moeller, and Chuan-Yuan Li

    Influence of Tumor pH on Therapeutic Response
    Chang W. Song, Robert Griffin, and Heon Joo Park

    Tumor Oxygenation and Treatment Response
    Sarah Jane Lunt and Richard P. Hill

    Oncogenes and Tumor Suppressor Genes in Therapeutic Resistance: The Role of Evolving Interrelationships Between Cancer Cells and Host Tissues
    Janusz W. Rak, Brenda Coomber, and Joanne L. Yu

    PET Imaging of Response and Resistance to Cancer Therapy
    David A. Mankoff and Kenneth A. Krohn

    Part II: Biological Resistance

    Cancer Stem Cells: Implications for Development of More Effective Therapies
    Ilia Mantle, Gabriela Dontu, Suling Liu, and Max S. Wicha

    Therapeutic Resistance in Leukemia
    William R. Waud

    Tumor Site Implantation and Animal Model Selection in Oncology
    Anibal A. Arjona and Enrique Alvarez

    In Vivo Resistance
    Beverly A. Teicher

    Characteristics of the Metastatic Phenotype: The Melanoma Experience
    Vladislava O. Melnikova and Menashe Bar-Eli

    The Microenvironment and Drug Resistance
    Patrice J. Morin

    Part III. Biochemical Resistance

    Glutathione and Glutathione S-Transferases in Drug Resistance
    Victoria J. Findlay, Danyelle M. Townsend, and Kenneth D. Tew

    Metallothioneins in Drug Resistance
    Faiyaz Notta and D. James Koropatnick

    Molecular Determinants of Intrinsic Multidrug Resistance in Cancer Cells and Tumors
    Elena Monti

    New and Revised Concepts in Multidrug Resistance: Sestamibi, SNPs, Substrates, and Stem Cells
    Susan E. Bates, John Deeken, Chaohong Fan, and Robert W. Robey

    Cisplatin Resistance: Molecular Basis of a Multifaceted Impediment
    Zahid H. Siddik

    Regulation of the Cellular Pharmacology and Cytotoxicity of Cisplatin by Copper Transporters
    Roohangiz Safaei and Stephen B. Howell

    Resistance to Taxanes
    Lee M. Greenberger and Deepak Sampath

    CpG Island Methylation and Drug Resistance
    Jens M. Teodoridis and Robert Brown

    De Novo and Acquired Resistance to Antitumor Alkylating Agents
    Lori A. Hazlehurst and William S. Dalton

    Resistance to Antiangiogenic Agents
    George W. Sledge, Jr., Kathy D. Miller, Bryan Schneider, and Christopher J. Sweeney

    Part IV. The Role of Hormones, Growth Factors, and Oncogenes

    Resistance to Antiestrogens
    Clodia Osipo and Ruth M. O'Regan

    Mechanisms of Glucocorticoid Actions and Resistance in Multiple Myeloma
    Varsha Gandhi and Beatriz Sanchez-Vega

    Herceptin Resistance
    Ingrid A. Mayer and Carlos L. Arteaga

    Role of TGF-b in Tumor Progression and Metastasis
    Jan Pinkas and Beverly A. Teicher

    p53-Based Immunotherapy of Cancer
    Albert B. DeLeo

    Response and Resistance to Ionizing Radiation
    Paul Dent, Adly Yacoub, Michael P. Hagan, and Steven Grant

    Amplification in DNA Copy Numbers as a Mechanism of Acquired Drug Resistance
    M. Jim Yen, Ie-Ming Shih, Victor E. Velculescu, and Tian-Li Wang

    Part V. Clinical Aspects of Resistance

    Cancer Chemotherapy: Clinical Evidence for Drug Resistance
    Mika A. Sovak and David R. Spriggs

    Molecular Profiling in Breast Cancer: Genomic Approaches Toward Tailored Cancer Therapies
    Kristin Kee and Jeffrey E. Green

    Tumor Immune Escape Mechanisms
    Yi Ting Koh, M. Luz García-Hernández, and W. Martin Kast

    Index