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Produktbild: Phase II Conjugation Enzymes and Transport Systems

Phase II Conjugation Enzymes and Transport Systems Volume 400

158,99 €

inkl. gesetzl. MwSt., Versandkostenfrei


Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

01.11.2005

Herausgeber

Helmut Sies + weitere

Verlag

Elsevier Science & Technology

Seitenzahl

736

Maße (L/B/H)

23,5/16,4/3,2 cm

Gewicht

1321 g

Sprache

Englisch

ISBN

978-0-12-182805-9

Beschreibung

Portrait

Helmut Sies is an Honorary Member of the American Society for Biochemistry and Molecular Biology. He received an Honorary Ph.D. from the University of Buenos Aires, Argentina in 1996. Dr. Sies is a member of the Northrhine-Westphalian Academy of Sciences, Germany, and a Corresponding Member of both the Academy of Sciences of Heidelberg, Germany, and the Academy of Medicine, Buenos Aires, Argentina. He has received many awards and prizes, including the FEBS Anniversary Prize awarded by the Federation of European Biochemical Societies, 1978; the Distinguished Foreign Scholar award, MASUA, 1985; the Silver Medal, Karolinska Institute, Stockholm, 1986; the Ernst Jung Preis fur Medizin, 1988; the Claudius-Galenus-Preis, 1990; and the ISFE-Preis, 1994. Dr. Sies sereves on the editorial board and advisory committee for twelve journals, has edited numerous books, and has published more than 400 original articles and chapters. He received his M.D. at the University of Munich in 1967 and currently serves as Full Professor and Chairman of the Department of Physiological Chemistry at the University of D sseldorf. Lester Packer received a PhD in Microbiology and Biochemistry in 1956 from Yale University. In 1961, he joined the University of California at Berkeley serving as Professor of Cell and Molecular Biology until 2000, and then was appointed Adjunct Professor, Pharmacology and Pharmaceutical Sciences, School of Pharmacy at the University of Southern California. Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de l'Ordre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California. He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology: Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the "Antioxidant Network regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cell's redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America.

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

01.11.2005

Herausgeber

Verlag

Elsevier Science & Technology

Seitenzahl

736

Maße (L/B/H)

23,5/16,4/3,2 cm

Gewicht

1321 g

Sprache

Englisch

ISBN

978-0-12-182805-9

EU-Ansprechpartner

Zeitfracht Medien GmbH
Ferdinand-Jühlke-Straße 7
99095 Erfurt
DE
produktsicherheit@zeitfracht.de

Herstelleradresse

Elsevier Science & Technology
125 London Wall
EC2Y 5AS London
GB
tradeorders@elsevier.com

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  • Produktbild: Phase II Conjugation Enzymes and Transport Systems
  • 1 UDP-glucuronosyltransferases: Gene structures of the UGT1 and UGT2 families; 2
    Identification and characterization of functional hepatocyte nuclear factor 1 binding sites in UDP-Glucuronosytransferase genes; 3 Substrate Specificity of Human Hepatic UDP-Glucuronosyltransferaes; 4 UDP-glucuronosytransferase (UGT) 1A6: structural, functional and regulatory aspects; 5 The Role of Ah Receptor in Induction of Human UDP-glucuronosyltransferase 1A1; 6 Regulation of the human UGT1A1 gene by nuclear receptors CAR, PXR and GR; 7 Isoform-selective probe substrates for in vitro studies of human UDP-glucuronosyltransferases; 8 Structure of UDP-glucuronosyltransferases in membranes; 9 Human SULT1A genes: Cloning and activity assays of the SULT1A promoters; 10 Vitamin D Receptor Regulation of the Steroid/Bile Acid Sulfotransferase SULT2A1; 11 Screening and characterizing human NAT2 variant; 12 Inactivation of human arylamine N-acetyltransferase 1 by hydrogen peroxide and peroxinitrite; 13 SULT and NAT in Mutagenicity Testing: Technical Aspects; 14 A comparative molecular field analysis (CoMFA) based approach to prediction of sulfotransferase catalytic specificity; 15 Glucuronidase deconjugation in inflammation; 16 Three-dimensional structures of sulfatases; 17 Estrogen sulfatase; 18 Analysis for localization of steroid sulfatase in human tissues; 19 Metabolism of Phytoestrogen Conjugates; 20 Coenzyme Q and phenolic conjugate metabolism; 21 Synthesis of bile acid CoA thioesters in the amino acid conjugation of bile acids; 22 Bile acid CoA: amino acid N-acyltransferase in the amino acid conjugation of bile acids; 23 Multidrug resistance protein 1-mediated export of glutathione and glutathione disulphide from brain astrocytes; 24 The genetics of ATP-binding cassette transporters; 25 Functional analysis of detergent-solubilized and membrane-reconstituted ABC Transporters; 26 Yeast ABC transporters - Cellular cleaning pumps; 27 High-speed screening of human ABC transporter function and genetic polymorphisms: New strategies in pharmacogenomics; 28 Coordinate transcriptional regulation of transport and metabolism; 29 Uptake and efflux transporters for anionic conjugates in human Hepatocytes; 30 Biliary canalicular transport systems: short-term regulation; 31 Inborn errors of biliary canalicular transport systems; 32 Epoxide Hydrolases - Structure, function, mechanism and assay; 33 Pregnane X receptor-mediated transcription; 34 Animal models of xenobiotic receptors in drug metabolism and diseases; 35 Cancer and molecular biomarkers of Phase 2