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Produktbild: Gene Therapy of Cancer
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Gene Therapy of Cancer Methods and Protocols

Aus der Reihe Methods in Molecular Biology
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144,99 € UVP 164,99 €

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

13.04.2009

Herausgeber

Wolfgang Walther + weitere

Verlag

Humana Press

Seitenzahl

738

Maße (L/B/H)

26,8/19,8/4,3 cm

Gewicht

1624 g

Auflage

2nd 2009 edition

Sprache

Englisch

ISBN

978-1-934115-85-5

Beschreibung

Rezension

From the reviews of the second edition:

"This book, authored by a number of prominent researchers in the field ... provides an overview of recent ground-breaking experimental and clinical concepts and protocols in cancer gene therapy. ... the editors and authors are to be commended for producing a well-organised, authoritative and succinct coverage of the vast area of gene therapy protocols. The materials are relevant, easy-to-follow and well-presented with good illustrations. Without doubt it will serve as a useful resource for those interested in this field, both scientists and clinicians ... ." (Han Hsi Wong and Yaohe Wang, Human Genetics, Vol. 128, July, 2010)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

13.04.2009

Herausgeber

Verlag

Humana Press

Seitenzahl

738

Maße (L/B/H)

26,8/19,8/4,3 cm

Gewicht

1624 g

Auflage

2nd 2009 edition

Sprache

Englisch

ISBN

978-1-934115-85-5

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Gene Therapy of Cancer
  • Section I: Experimental Approaches in Cancer Gene Therapy

    Subsection A: Introduction

    1. The Development of Gene Therapy: From Monogenic Recessive Disorders to Complex Diseases such as Cancer
    Jean-Pierre Gillet, Benjamin Macadangdang, Robert L. Fathke, Michael M. Gottesman, and Chava Kimchi-Sarfaty

    Subsection B: Vectorology for Cancer Gene Therapy

    2. Designing Adenoviral Vectors for Tumor-Specific Targeting
    Ramon Alemany

    3. Analysis of HSV Oncolytic Virotherapy in Organotypic Cultures
    Giulia Fulci and Brent Passer

    4. Use of Minicircle Plasmids for Gene Therapy
    Peter Mayrhofer, Martin Schleef, and Wolfgang Jechlinger

    5. Transposable Elements as Plasmid-Based Vectors for Long-Term Gene Transfer into Tumors
    John R. Ohlfest, Zoltán Ivics, and Zsuzsanna Izsvák

    6. Designing Plasmid Vectors
    Oleg Tolmachov

    7. Development of Bacterial Vectors for Tumor-Targeted Gene Therapy
    Li-Jun Jia and Zi-Chun Hua

    Subsection C: Nonviral Transfer Technologies in Cancer Gene Therapy

    8. Electroporative Gene Transfer
    Marco Schmeer

    9. Gene Gun Delivery Systems for Cancer Vaccine Approaches
    Kandan Aravindaram and Ning Sun Yang

    10. Ultrasound-Mediated Gene Transfection
    Loreto B. Feril, Jr.

    11. Nonviral Jet-Injection Technology for Intratumoral in vivo Gene Transfer of Naked DNA
    Wolfgang Walther, Iduna Fichtner, Peter M. Schlag, and Ulrike S. Stein

    Subsection D: Experimental Studies in Cancer Gene Therapy

    12. Methods for Constructing and Evaluating Anti-Tumor DNA Vaccines
    Brian M. Olson and Douglas G. McNeel

    13. Immunity of Lentiviral Vector-Modified Dendritic Cells
    Shuhong Han andLung-Ji Chang

    14. Saporin Suicide Gene Therapy
    Natasa Zarovni, Riccardo Vago, and Maria Serena Fabbrini

    15. Utilizing In Vivo Biopanning for the Development of Radiation-Guided Drug Delivery Systems
    Jerry J. Jaboin, Zhaozhong Han, and Dennis E. Hallahan

    16. Chemosensitization of Tumor Cells: Inactivation of Nuclear Factor kB Associated with Chemosensitivity in Melanoma Cells after the Combination Treatment of E2F-1 and Doxorubicin
    Hongying Hao, H. Sam Zhou, and Kelly M. McMasters

    17. Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
    Thomas S. Griffith

    18. Silencing Epidermal Growth Factor Receptor (EGFR) by RNA Interference (RNAi) in Glioma
    Chunsheng Kang, Peiyu Pu, and Hao Jiang

    19. Delivery of Phosphorodiamidate Morpholino Antisense Oligomers in Cancer Cells
    Gayathri R. Devi

    20. Use of RNA Aptamers for the Modulation of Cancer Cell Signaling
    Sunjoo Jeong, Hee Kyu Lee, and Mee Young Kim

    21. G-Rich Oligonucleotides (GROs) for Cancer Treatment
    Paula J. Bates, Enid W. Choi, and Lalitha V. Nayak

    Section II: Clinical Approaches in Cancer Gene Therapy

    Subsection A: Requirements for Clinical Gene Therapy Trials

    22. Regulatory Aspects for Translating Gene Therapy Research into the Clinic
    Carolyn M. Laurencot and Sheryl Ruppel

    23. Ethics of Cancer Gene Transfer Clinical Research
    Jonathan Kimmelman

    24. Virus Production for Clinical Gene Therapy
    Tiago Vicente, Cristina Peixoto, and Manuel J. T. Carrondo

    25. Production of Plasmid DNA as Pharmaceutical
    Martin Schleef and Markus Blaesen

    Subsection B: Clinical Protocols in Cancer Gene Therapy

    26. Gene Immunotherapy for Non-Small Cell Lung Cancer
    John